Results 251 to 260 of about 1,096,418 (305)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Next-generation sequencing: Driving a paradigm shift from pathogen detection to systems-level analysis. [PDF]

Infect Med (Beijing)
Peng Y, Wang Y, Liu L, Liu Y, Yu Y, Sun R, Yu Z.   +6 more
europepmc   +1 more source

Next-generation sequencing in newborn screening: Current status, challenges, and future perspectives. [PDF]

Pediatr Investig
Huang Z, Zhou W.
europepmc   +1 more source

Next Generation Sequencing of Tracheal Aspirates in Children With Tracheostomy A Prospective Case-Control Study. [PDF]

Pediatr Pulmonol
Brensing P, Lutynski J, Hilder M, Brenner T, Mazzitelli S, Grumaz S, Stehling F.   +6 more
europepmc   +1 more source

Analytic and Diagnostic Validation of a Targeted Next-Generation Sequencing Panel for Common and Emerging Swine Respiratory Pathogens. [PDF]

Microorganisms
Elshafie NO, Wilkes RP.
europepmc   +1 more source

<i>CIC-DUX4</i> Rearranged Gastric Sarcoma Confirmed by Next-Generation Sequencing: A Case Report and Review of Literature. [PDF]

Clin Case Rep
Hasegawa H, Takeno A, Higashiura R, Sakakibara Y, Koba M, Hirose Y, Mori K, Hirao M, Mano M, Sakamori R.   +9 more
europepmc   +1 more source

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Next-generation DNA sequencing

Nature Biotechnology, 2008
DNA sequence represents a single format onto which a broad range of biological phenomena can be projected for high-throughput data collection. Over the past three years, massively parallel DNA sequencing platforms have become widely available, reducing the cost of DNA sequencing by over two orders of magnitude, and democratizing the field by putting ...
J. Shendure, Hanlee P. Ji
semanticscholar   +3 more sources