Results 41 to 50 of about 270,662 (312)

The Regulation of Commodity Options [PDF]

, 1978
To outline further genetic mechanisms of transformation from follicular lymphoma (FL) to diffuse large B-cell lymphoma (DLBCL), we have performed whole genome array-CGH in 81 tumors from 60 patients [29 de novo DLBCL (dnDLBCL), 31 transformed DLBCL ...
Berglund, Mattias, Collins, V. Peter, Dinets, Andrii, Ichimura, Koichi, Kwiecinska, Anna, Lagercrantz, Svetlana Bajalica, Larsson, Catharina, Porwit, Anna, Sulaiman, Luqman   +8 more
core   +3 more sources

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Interactions among oscillatory pathways in NF-kappa B signaling [PDF]

BMC Systems Biology, 2011
Sustained stimulation with tumour necrosis factor alpha (TNF-alpha) induces substantial oscillations--observed at both the single cell and population levels--in the nuclear factor kappa B (NF-kappa B) system. Although the mechanism has not yet been elucidated fully, a core system has been identified consisting of a negative feedback loop involving NF ...
Wang, Yunjiao, Paszek, Pawel, Horton, Caroline A., Kell, Douglas B., White, Michael R H, Broomhead, David S., Muldoon, Mark R.   +6 more
openaire   +6 more sources

Pro-inflammatory Signaling in a 3D Organotypic Skin Model after Low LET Irradiation-NF-kappa B, COX-2 Activation, and Impact on Cell Differentiation [PDF]

, 2017
Nearly 85% of radiotherapy patients develop acute radiation dermatitis, which is an inflammatory reaction of the skin at the treatment field and in the surrounding area.
Acheva, Anna, Prise, Kevin M., Schettino, Giuseppe   +2 more
core   +2 more sources

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

The NFκB Expression on Apical Dental Granuloma: An Immunohistochemistry Analysis

Clinical, Cosmetic and Investigational Dentistry, 2020
Risya Cilmiaty,1 Nirawati Pribadi,2 Mandojo Rukmo,2 Meircurius Dwi Condro Surboyo3 1Department of Oral Disease, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia; 2Department of Conservative Dentistry, Faculty of Dental Medicine ...
Cilmiaty R, Pribadi N, Rukmo M, Surboyo MDC   +3 more
doaj  

Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters [PDF]

Journal of Virology, 1995
During human cytomegalovirus (HCMV) infection, a series of regulated events take place following virus binding and entry into the cell, including the upregulation of cellular transcription factors, such as NF-kappa B, which play an essential role in the viral life cycle. We show here that NF-kappa B message is induced during HCMV infection and that the
A D, Yurochko, T F, Kowalik, S M, Huong, E S, Huang   +3 more
openaire   +2 more sources

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens [PDF]

, 2012
Members of the intracellular nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR) family contribute to immune responses through activation of nuclear factor-kappa B (NF-kappa B), type I interferon and inflammasome signalling(1).
C van Ooij, DA Portnoy, E Elinav, E Scallan, EM Creagh, GY Chen, J Henao-Mejia, JM Grenier, John Bertin, John R. Lukens, K Hybiske, K Meixenberger, KS Kobayashi, L Franchi, M Lara-Tejero, MH Zaki, MM Stevenson, Mohamed Lamkanfi, MR Waterfield, NV Serbina, P Broz, Paras K. Anand, Peter Vogel, PK Anand, R. K. Subbarao Malireddi, S Normand, SC Corr, SE Girardin, TD Kanneganti, TD Kanneganti, Thirumala-Devi Kanneganti, V Pétrilli   +31 more
core   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor [PDF]

, 2002
Negative selection eliminates thymocytes bearing autoreactive T cell receptors (TCR) via an apoptotic mechanism. We have cloned an inhibitor of NF-kappa B, I kappa BNS, which is rapidly expressed upon TCR-triggered but not dexamethasone- or gamma ...
Fiorini, Emma, Reche, Pedro A
core