Results 21 to 30 of about 28,866 (196)

Distinct genomic subclasses of high-grade/progressive meningiomas – NF2-associated, NF2-exclusive, and NF2-agnostic

open access: yes, 2021
72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für ...
Prilop, I   +7 more
openaire   +1 more source

Dualities in 4D Theories with Product Gauge Groups from Brane Configurations [PDF]

open access: yes, 1997
We study brane configurations which correspond to N=1 field theories in four dimensions. By inverting the order of the NS 5-branes and D6-branes, a check on dualities in four dimensional theories can be made.
Tatar, Radu
core   +2 more sources

NF2 inhibits proliferation and cancer stemness in breast cancer

open access: yesOpen Medicine, 2020
Previous studies have shown that NF2 plays a key role in tumorigenesis. NF2 has been illustrated to be downregulated in several types of human cancer. However, the role of NF2 in breast cancer remains unclear.
Wang Zhibao   +3 more
doaj   +1 more source

Asymptotically Safe Standard Model via Vector-Like Fermions [PDF]

open access: yes, 2017
We construct asymptotically safe extensions of the Standard Model by adding gauged vector-like fermions. Using large number-of-flavour techniques we argue that all gauge couplings, including the hypercharge and, under certain conditions, the Higgs ...
Mann, Robert   +5 more
core   +3 more sources

Emergence of scalar matter from spinfoam model [PDF]

open access: yes, 2009
A spinfoam model of 3D gravity non-minimally coupled with a scalar field is studied. By discretization of the scalar field, the model is worked out precisely in a purely combinational way.
Ma, Yongge, Xu, Peng
core   +1 more source

NF2 signaling pathway plays a pro-apoptotic role in β-adrenergic receptor stimulated cardiac myocyte apoptosis.

open access: yesPLoS ONE, 2018
Methods and resultsTreatment of adult rat ventricular myocytes (ARVMs) with β-AR agonist (isoproterenol) for 15 min increased phosphorylation (serine-518) and sumoylation of NF2.
Suman Dalal   +3 more
doaj   +1 more source

Role of NF2 Haploinsufficiency in NF2‐associated Polyneuropathy

open access: yesBrain Pathology, 2007
Neurofibromatosis 2 (NF2) is a hereditary tumor disease characterized by bilateral vestibular schwannomas. Polyneuropathy seems to occur quite frequently in NF2 and in most cases, the etiology of this neuropathy is unclear, especially when the neuropathy is symmetric. NF2 is believed to follow the two‐hit hypothesis.
Clemens O, Hanemann   +2 more
openaire   +3 more sources

Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt Signalling. [PDF]

open access: yes, 2016
Research over the last decade recognized the importance of novel molecular pathways in pathogenesis of intracranial meningiomas. In this review, we focus on human brain tumours meningiomas and the involvement of Wnt signalling pathway genes and proteins ...
Kafka, Anja   +2 more
core   +2 more sources

The genetic landscape and possible therapeutics of neurofibromatosis type 2

open access: yesCancer Cell International, 2023
Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development of multiple benign tumors in the nervous system. The most common tumors associated with NF2 are bilateral vestibular schwannoma, meningioma, and ependymoma.
Mohammad Amin Ghalavand   +5 more
doaj   +1 more source

Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic impact integrated with extent of resection, tumour location, and Ki-67 index

open access: yesActa Neuropathologica Communications, 2022
NF2 alteration is the most commonly–found genetic abnormality in meningiomas and is known to initiate events for aggressive-type meningiomas. Whereas the prognosis of meningiomas differs depending on their epigenomic/transcriptomic profile, the effect of
Yu Teranishi   +16 more
doaj   +1 more source

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