Results 71 to 80 of about 13,804 (209)
Lewy bodies are surrounded by granulovacuolar degeneration bodies in dementia with Lewy bodies
Brain Pathology, EarlyView.Here, we report Lewy bodies (LBs) to be enriched for tau‐laden granulovacuolar degeneration bodies (GVBs), suggesting a potential mechanistic interface between α‐synuclein and tau pathology in dementia with Lewy bodies (DLB). Abstract Lewy bodies (LBs), composed primarily of aggregated α‐synuclein (α‐syn), are the pathological hallmark of Lewy body ...
Searlait Thom +7 more
wiley +1 more source
Brain Pathology, EarlyView.This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata +4 more
wiley +1 more source
CoRRNon-fungible tokens (NFTs) on Ethereum currently follow a binary mobility paradigm: ERC-721 enables unrestricted transfers, whereas SBTs (ERC-5192) prohibit transfers entirely. We identify a design gap in which no standard mechanism supports bounded transferability, where ownership mobility is allowed but limited to a finite number of programmable ...
Qin Wang 0008 +3 more
openaire +2 more sources
Artificial intelligence–based 3D segmentation of tangle‐associated TDP‐43 in neurodegeneration
Brain Pathology, EarlyView.Multiplex immunostaining of anti‐phosphorylated TDP‐43, tau (AT8, pS396, TauC3, MN423, GT38), and Thioflavin S combined with AI‐based object recognition, reconstruction, and TAT maturation analysis pipeline in limbic regions revealed that distinct aggregation and tangle maturation patterns underscored region‐specific dynamics in the neurodegenerative ...
Gokhan Uruk +6 more
wiley +1 more source
M/C Journal, 2022 Depending on your perspective, Non-Fungible Token (NFT) artworks are inaugurating an exciting new chapter in the history of art, or a dangerous new chapter in the history of online market bubbles. NFTs index artworks, and are typically strings of characters stored on a blockchain such as Ethereum.
openaire +1 more source
Survey on Visualization of Information Diffusion over Networks
Computer Graphics Forum, EarlyView.Abstract Information Diffusion (ID) describes how a value (e.g., a pathogen, a rumor, a packet) spreads through an underlying “medium” network of elements (e.g., a social or computer network). Understanding the information diffusion process is essential to predicting trends, controlling misinformation, and enhancing decision‐making as well as ...
T. Baumgartl +8 more
wiley +1 more source
Similar or Different? Configurations of Authenticity Across Museum Types
Curator: The Museum Journal, EarlyView.ABSTRACT Authenticity is traditionally regarded as playing a crucial role in museums, science centers, and memorials. However, despite this fact, authenticity has very different meanings in different (institutional) settings. This complicates shared communications across museum practices.
S. Schwan +18 more
wiley +1 more source
Financial Markets, Institutions &Instruments, EarlyView.ABSTRACT This paper studies the determinants of banks' and fintech companies' systemic risk. We adopt both a systemic and firm‐level perspective and consider not only factors traditionally used to explain systemic riskiness, which have never been applied to the fintech sector, but also the new potential source of instability, for both banks and fintech
Domenico Curcio +3 more
wiley +1 more source
The Emerging Role of UCHL1 in Neurological and Musculoskeletal Diseases
Immunology &Cell Biology, EarlyView.UCHL1‐associated pathology. The pathological role of UCHL1 in multisystem diseases, including cancer, neurological, musculoskeletal and cardiovascular disorders. ABSTRACT Ubiquitin C‐terminal hydrolase L1 (UCHL1) is a highly conserved deubiquitinating enzyme that has transitioned from being viewed as a “brain‐specific” protein to a global regulator of ...
Ru Feng +3 more
wiley +1 more source