Results 91 to 100 of about 13,804 (209)

Dеmystification of propеrty rights in thе contеxt of thе digital transformation of thе еconomy

RUDN Journal of Law
Thе rеsеarch rеlеvancе liеs in thе intеrsеction of thе classical civil problеm of thе lеgal naturе of propеrty rights and thе еvolving landscapе of digital tеchnologiеs, which has givеn risе to propеrty rights taking on a digital form (digital rights ...
Anatoly V. Efimov
doaj   +1 more source

Increased Binding of [18F]Nifene, a PET Imaging Probe for α4β2* Nicotinic Acetylcholinergic Receptors in Hippocampus–Subiculum of Postmortem Human Parkinson's Disease Brain

Synapse, Volume 80, Issue 5, September 2026.
[18F]Nifene, a PET imaging probe for α4β2* nicotinic acetylcholine receptors, was used to discretely measure changes in hippocampus (HP) and subiculum (SUB) of postmortem Parkinson's disease (PD) cases compared to cognitively normal (CN) cases. Significant increased [18F]nifene binding in PD was observed.
Jogeshwar Mukherjee, Fariha Karim, Allyson Ngo, Christopher Liang, Geidy E. Serrano, Thomas G. Beach   +5 more
wiley   +1 more source

Valuation and Volatility of Virtual Properties in Metaverse: Exploring New Market Opportunities and Speculative Dynamics Based on Decentraland

Journal of Metaverse
Existing reality has been repeatedly subjected to multifaceted and multidimensional analyses. However, alongside it, a virtual reality exists, populated with virtual art, objects in games, cyber-pets, and virtual properties, collectively worth billions ...
Dawid Narowski, Celso Santos, Lukasz Borowski, Michal Apollo, Kamil Maciuk   +4 more
doaj   +1 more source

Maximizing the Economic, Environmental, and Social Impact of the Metaverse

Thunderbird International Business Review, Volume 68, Issue 5, Page 677-690, September/October 2026.
ABSTRACT The metaverse is a transformative digital ecosystem with the potential to redefine economic, environmental, and social systems. This qualitative study examines how the metaverse and its enabling technologies—such as AR/VR, blockchain, and AI—might evolve to influence sustainability. Drawing on semi‐structured interviews with global experts and
Alessandro Lanteri, Mark Esposito, Massimiliano Cappuccio   +2 more
wiley   +1 more source

Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease

Brain Pathology, Volume 36, Issue 5, September 2026.
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Conjoint analysis of key determinants of consumer purchase intentions for profile picture non-fungible tokens

Humanities & Social Sciences Communications
Since 2021, interest in non-fungible tokens (NFTs) and associated trading volume have increased substantially, as celebrities increasingly adopted profile picture non-fungible tokens (PFP NFTs) for their social media profile images.
Yongki Baek, Joohee Kim, Daeho Lee, Jungwoo Shin, Yunseon Na, Mideum Choi   +5 more
doaj   +1 more source

Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology

Brain Pathology, Volume 36, Issue 5, September 2026.
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz, Sylwia Tarka, Michał Grzegorczyk, Radosław Rzepliński, Teresa Wierzba‐Bobrowicz, Tomasz Stępień   +5 more
wiley   +1 more source

After the Hype: Resilience Seeking in Emerging Technology Ecosystems

Journal of Product Innovation Management, Volume 43, Issue 5, Page 793-826, September 2026.
ABSTRACT Academic Summary Hype often helps emerging technology ecosystems gain early support for their innovative value propositions, but the initial excitement around the technology typically vanishes at some point. This decrease in excitement and support may lead some ecosystems to fail while others are resilient and recover.
Fiona Schweitzer, Stacey L. Howard‐Malek, Maximilian Palmié   +2 more
wiley   +1 more source

Intranasal Administration of Isoeugenol Improves Memory Deficits in APP/PS1 Old Mice—A Role Beyond Nrf2 Activation?

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva, Sónia Silva, Jéssica Macedo, Patrícia Moreira, Diana Baptista, Joana Bicker, Ana Fortuna, Joana Liberal, Beatriz Rodrigues, Rosa Resende, Inês Vitorino, Armanda E. Santos, Bruno Miguel Neves, Cláudia Pereira, Maria Teresa Cruz   +14 more
wiley   +1 more source

Rational Design of Multifunctional Tacrine Derivatives as Candidates for the Treatment of Alzheimer and Parkinson Diseases

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
We present a set of multifunctional tacrine derivatives, designed with the CADMA‐Chem protocol, aimed for Alzheimer and Parkinson diseases. Of the tacrines designed, TAC‐674 and TAC‐678 are the best candidates to act as multifunctional antioxidants and neuroprotectors for Alzheimer and Parkinson diseases, respectively.
Eugenia Dzib, Luis Felipe Hernández‐Ayala, Silvana Silva‐Aguirre, Annia Galano   +3 more
wiley   +1 more source