Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato +2 more
wiley +1 more source
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya +5 more
wiley +1 more source
ABSTRACT Surprise marketing, characterized by unexpected tactics such as blind boxes and spontaneous discounts, captivates consumers by sparking curiosity and participation. Despite increasing industry use, scholarly research remains fragmented and limited.
Xin‐Jean Lim +2 more
wiley +1 more source
The study found that SARS‐CoV‐2 Omicron infection causes region‐specific inflammatory, immune, synaptic, and signaling disorders in the brain, and the predicted kinases and differentially expressed proteins may serve as potential targets for COVID‐19‐related drug discovery.
Qiaochu Wang +8 more
wiley +1 more source
Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley +1 more source
Demonstration of Anaplasma marginale transmission to cattle through the intra-transstadial and by unfed larvae of Rhipicephalus microplus routes, with subsequent calculation of infection rates. [PDF]
Heller LM +12 more
europepmc +1 more source
Nanoarchitectonics of nitrogen/selenium functionalized Co-ZIF-9(III) nanorod/nanosheet for nanomolar-level detection of nitrofurantoin antibiotics in environmental and biomedical samples. [PDF]
Tyagaraj HB +11 more
europepmc +1 more source
Taurine supplementation in fish meal-free diet improved growth, alleviated hypoxic-induced gill injury associating with Ca<sup>2+</sup> homeostasis and endoplasmic reticulum stress in sub-adult grass carp (<i>Ctenopharyngodon idella</i>). [PDF]
Yan J +10 more
europepmc +1 more source
Dissolved oxygen limitation and <i>Pythium</i> root rot in strawberry NFT systems: mechanisms, research gaps, and prospects for substrate-free production. [PDF]
Scott S, Villouta C.
europepmc +1 more source
Fabrication of nitrofurantoin-loaded chitosan-silver nanoparticles for the treatment of urinary tract infections. [PDF]
Ningaraju GN +7 more
europepmc +1 more source

