Results 101 to 110 of about 13,804 (209)

Characterization of [18F]SMBT‐1 binding substrates in Alzheimer's disease and related disorders: A postmortem biochemical and immunohistochemical study

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Neuroimaging studies report associations of amyloid beta (Aβ) positron emission tomography (PET) with [18F](S)‐(2‐methylpyrid‐5‐yl)‐6‐[(3‐fluoro‐2‐hydroxy)propoxy]quinoline ([18F]SMBT‐1), a novel reactive astrogliosis surrogate radiotracer with high affinity for monoamine oxidase B (MAO‐B) in Alzheimer's disease (AD).
Eric E. Abrahamson, Julia K. Kofler, Oscar L. Lopez, Anne D. Cohen, Alexandra Gogola, Howard J. Aizenstein, Thomas K. Karikari, Elliott J. Mufson, Victor L. Villemange, Milos D. Ikonomovic   +9 more
wiley   +1 more source

Legal nature of digital avatars of metaverses: civil-legal status and problems of criminal-legal protection

Russian Journal of Economics and Law
Objective: to resolve the conceptual uncertainty of the civil-law status of digital avatars in the metaverse and related problems of their criminal-legal protection, in particular, to develop criteria for distinguishing property, contractual and ...
A. A. Nagornyy
doaj   +1 more source

Brain morphometry patterns in the presence of Alzheimer's disease and/or LATE neuropathologic changes

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Alzheimer's disease neuropathologic change (ADNC) and limbic‐predominant age‐related transactive response DNA‐binding protein 43 kDa (TDP‐43) encephalopathy neuropathologic change (LATENC) are common in older adults, yet differences in brain morphometry patterns when one or both pathologies are present remain unclear.
Khalid Saifullah, Abdur Raquib Ridwan, Arnold M. Evia, Sue E. Leurgans, Maude Wagner, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +7 more
wiley   +1 more source

Correlative Relationships Between Cryptoassets and Price Bubbles: Risk and Contagion Dynamics of Digital Markets

İktisat Politikası Araştırmaları Dergisi
The development of cryptographic digital markets and the growing number of investors have generated concerns about the formation of price bubbles. We can describe the formation of a price bubble as a manifestation of the pricing paradox, characterised by
Oğuzhan Ece, Bülent Diclehan Çadırcı   +1 more
doaj   +1 more source

Gantenerumab for Early Alzheimer's Disease: An Updated Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 16, Issue 8, August 2026.
This updated systematic review and meta‐analysis shows that gantenerumab significantly reduces cerebral amyloid burden and modestly improves functional and cognitive outcomes in early Alzheimer's disease, but these benefits are accompanied by an increased risk of amyloid‐related imaging abnormalities, highlighting a cautious benefit–risk balance ...
Muhammad Nouman Javed, Saim Mahmood Khan, Smaher Mustafa, Amna Mujtaba, Hassaan Amin, Naveen Azhar, Abdullah Hameed, Alaa Zayed, Maliha Khalid, Jawairya Muhammad Hussain   +9 more
wiley   +1 more source

Emerging Trends and Hot Spots in Tauopathy Research (2003–2025): A Bibliometric Analysis

Brain and Behavior, Volume 16, Issue 8, August 2026.
This bibliometric analysis systematically evaluated global research trends in tauopathy from 2003 to 2025. Using bibliometric methods, including R package bibliometrix, VOSviewer, and Scimago Graphica, we identified publication trends, influential countries, institutions, authors, journals, and emerging research themes.
Si‐Yao Zhang, Hui‐Jie Ren, Hao‐Yu Liu, Shu‐Ying Xu, Yong‐Jun Peng   +4 more
wiley   +1 more source

Water‐Mediated Phosphoryl Wires Stabilize Pathological Tau Fibrils

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
Extended 1D phosphoryl “wires” stabilize in‐register amyloid tau fibrils, as demonstrated by multiple‐quantum spin‐counting NMR, TEM, and MD simulations, using fibrils of tau peptide jR2R3‐P301L (tau295–313) with phosphorylation at S305 or Y310. ABSTRACT Hyperphosphorylation of tau is a hallmark of tauopathies, with specific phosphorylation sites ...
Lokeswara Rao Potnuru, Austin DuBose, Fiona Mon, Mesopotamia S. Nowotarski, Michael Vigers, Boqin Zhang, Chung‐Ta Han, John E. Straub, Songi Han   +8 more
wiley   +2 more sources

NFT Sanatının Sanat Piyasasına Etkisi: Dün, Bugün, Gelecek Perspektifleri

Art and Interpretation
Sanat eserlerinin yegâne özelliği biricik olmasıdır, aynısının ikincisi yoktur. Dünyada tek olduğu için değerlidir. Biricik, özgün, tek olarak adlandırılanlar, kendilerinden öncekilerin farklı bir biçimde sunumudur.
Derya Aydoğan
doaj  

L’arte digitale quale futuro veicolo della contemporaneità: gli NFT (Non Fungible Token)

Conservation Science in Cultural Heritage
Gli NFT rappresentano il principale strumento per la certificazione dell’autenticità e della proprietà di opere d'arte digitali. Un NFT è un certificato digitale immutabile e protetto tramite blockchain, una tecnologia sicura che garantisce l’integrità ...
Salvatore Lorusso, Luca Gugliermetti, Federico Cinquepalmi   +2 more
doaj   +1 more source

A Novel Nogo‐A Receptor Antagonist Peptide Impedes Alzheimer's Disease Pathology by Nogo‐A/NgR/ROCK Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
NAP2, a NgR1 antagonist peptide, improved cognition in APP/PS1 mice, reduced Aβ plaques and tau hyperphosphorylation, increased dendritic spine density, and alleviated mitochondrial damage, acting through inhibition of the Nogo‐A/NgR/ROCK pathway, highlighting its therapeutic potential for Alzheimer's disease.
Zheng Zhang, Huimin Tan, Fang Shi, Jiajia Dai, Weilong Ding, Junliang Li, Yuke Wang, Rui Yang, Xinke Xu, Cheng Chen, Fei Xiao, Li‐an Huang, Xiaoyan Liu, Rui Liao, Li Yan   +14 more
wiley   +1 more source