Results 111 to 120 of about 17,594 (242)

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

A Comparative Study of Aging and Cortical Folding in Chimpanzees and Olive Baboons

American Journal of Primatology, Volume 88, Issue 7, July 2026.
This figure shows 3D renderings of a chimpanzee (top) and olive baboon (bottom) brain with each sulcus label used in this study. After sulci were labeled, we exported metrics including mean depth and fold opening (width) of each sulcus to examine age‐related changes in these measures, as well as sex differences within species.
William D. Hopkins, Angela Achorn, Michele M. Mulholland, Elizabeth Magden, Steven J. Schapiro, Courtney L. Fults, Jean‐Francois Mangin, Adrien Meguerditchian   +7 more
wiley   +1 more source

The Fiction of NFTs and Copyright Infringement

, 2022
In the first quarter of 2021, the sales of art in the form of Non-Fungible Tokens (“NFTs”) reached over $200 billion dollars. The arrival of NFTs in the mainstream art market has profoundly shaped the way artists exploit their works.
Behzadi, Emily T.
core   +1 more source

Patient‐derived forebrain cortical organoids reveal biphasic tau–MAP6–microtubule axis dysfunction in tauopathy

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION In frontotemporal dementia (FTD), tau detaches from axonal microtubules and forms pathological aggregates. Rather than stabilizing microtubules, tau promotes labile microtubule domains, redefining its role in neurodegeneration and underscoring the need for human models that capture temporal disease progression.
Xiaohuan Sun, Skandha Ramakrishnan, Victor C. Ogbolu, Nicholas M. Kanaan, Celeste M. Karch, Peter W. Baas, Liang Qiang   +6 more
wiley   +1 more source

Elimination of tau tangles and soluble aggregates with the small molecule ACI‐16664 prevents neurodegeneration in vivo

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Pathological tau aggregates are key therapeutic targets in Alzheimer's disease (AD), but current approaches face limitations including poor intracellular penetration, lack of selectivity for aggregated over physiological tau, or reliance on invasive administration.
Nicolas Preitner, Véronique Dehlinger, Patrick Rodriguez, Kerstin Fabbri, Yvan Varisco, Matteo Pigni, Alessandra Lovison, Lucas Münzenmaier, Kasia Piorkowska, Aline Fuchs, Nadine Ait‐Bouziad, Nicolas Fournier, Sandra Jepaul, Jérôme Molette, Emanuele Gabellieri, Vincent Darmency, Sonia Poli, Andrea Pfeifer, Marie Kosco‐Vilbois, Francesca Capotosti   +19 more
wiley   +1 more source

A nascent market for digital assets: Exploration of consumer value of NFTs

Digital Business
Despite widespread academic and practitioner interest in non-fungible tokens (NFTs) as a form of digital assets, little is known about how consumers perceive NFT value. This exploratory research investigates why people create, trade or collect NFTs, what
Tatiana Zalan, Elissar Toufaily
doaj   +1 more source

Evaluation of CSF and plasma tau species as fluid surrogate candidates for tau PET in prodromal to moderate Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Positron emission tomography (PET) is a valuable tool for assessing tau pathology in Alzheimer's disease (AD), but it is not widely accessible. Clarifying the relationship between fluid tau species and tau PET in AD may allow for the identification of fluid biomarkers that could serve as more accessible surrogates for tau PET ...
Julie Lee, Emily Olafson, Balazs Toth, Ellen Casavant, Stephen Schauer, Tobias Bittner, Matthew R. Meyer, Philip B. Verghese, Venky Venkatesh, Tim West, Joel B. Braunstein, Anne Biever, Emilia Calderon, Melanie Mandl, Anna Bayfield, Casper C. Hoogenraad, Edmond Teng, Cecilia Monteiro, Veronica G. Anania, Sandra M. Sanabria Bohórquez, Felix L. Yeh   +20 more
wiley   +1 more source

Exploring the disruptive potential of non fungible tokens (NFTs) in the reconfiguration of urban spaces

npj Urban Sustainability
This essay examines the transformative potential of Non-Fungible Tokens (NFTs) in urban environments, specifically regarding ownership structures, management processes, and civic participation.
Ehsan Dorostkar, Keramatollah Ziari
doaj   +1 more source

Use Case of Non-Fungible Tokens (NFTs): A Blockchain Approach for Geological Data Dissemination

J
The application of blockchain technology and Non-Fungible Tokens (NFTs) into geology offers potential for the preservation, management, and dissemination of geological data.
Muhammad Aufaristama
doaj   +1 more source

Sleep fragmentation correlates with amyloid beta deposition at brain autopsy

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Poor sleep is a symptom and candidate risk factor for Alzheimer's disease (AD). We investigated whether objective and subjective longitudinal sleep measures correlated with AD pathology at brain autopsy. METHODS Rush Memory and Aging Project (MAP) participants (n = 798; Meanage at baseline = 81.72) underwent annual evaluation with
Mark A. Rudolf, Yee To Ng, Andrew P. Lieberman   +2 more
wiley   +1 more source