Results 21 to 30 of about 382,279 (282)

Comparative of clinical performance between next-generation sequencing and standard blood culture diagnostic method in patients suffering from sepsis

Journal of Microbiology, Immunology and Infection, 2022
Background: Next-generation sequencing (NGS) is a massively unbiased sequencing technology. The objective of this study was to evaluate the performance of NGS-based approach in the detection of microorganisms from septic patients and compare with results
Ing-Kit Lee, Jen-Ping Chang, Wen-Chi Huang, Chien-Hsiang Tai, Huang-Tu Wu, Chih-Hung Chi   +5 more
doaj   +1 more source

Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons

Scientific Reports, 2021
A strong focus on sex-related differences has arisen recently in neurobiology, but most investigations focus on brain function in vivo, ignoring common experimental models like cultured neurons.
Sinem M. Sertel, Wiebke Blumenstein, Sunit Mandad, Orr Shomroni, Gabriela Salinas, Silvio O. Rizzoli   +5 more
doaj   +1 more source

Development and Validation of Targeted Next-Generation Sequencing Panels for Detection of Germline Variants in Inherited Diseases. [PDF]

, 2017
Context.-The number of targeted next-generation sequencing (NGS) panels for genetic diseases offered by clinical laboratories is rapidly increasing. Before an NGS-based test is implemented in a clinical laboratory, appropriate validation studies are ...
Ferreira-Gonzalez, Andrea, Funke, Birgit, Hegde, Madhuri, Mao, Rong, Murrell, Jill, Santani, Avni, Voelkerding, Karl V., Weck, Karen E., Yu, Zhenming   +8 more
core   +3 more sources

BamView: visualizing and interpretation of next-generation sequencing read alignments. [PDF]

, 2012
So-called next-generation sequencing (NGS) has provided the ability to sequence on a massive scale at low cost, enabling biologists to perform powerful experiments and gain insight into biological processes.
Berriman, Matthew, Carver, Tim, Harris, Simon R., McQuillan, Jacqueline A., Otto, Thomas D., Parkhill, Julian   +5 more
core   +1 more source

MarkerMiner 1.0: a new application for phylogenetic marker development using angiosperm transcriptomes [PDF]

, 2015
Premise of the study: Targeted sequencing using next-generation sequencing (NGS) platforms offers enormous potential for plant systematics by enabling economical acquisition of multilocus data sets that can resolve difficult phylogenetic problems ...
Berbazuk, W Brad, Chamala, Srikar, De Smet, Riet, García, Nicolás, Godden, Grant T, Jordon-Thaden, Ingrid E, Krishnakumar, Vivek, Soltis, Douglas E, Soltis, Pamela S   +8 more
core   +3 more sources

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]

, 2010
Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex, Altschul, Anja Joachim, Ashburner, Bentley, Bethony, Björnberg, Blaxter, Boag, Bronwyn E. Campbell, Caffrey, Campbell, Cantacessi, Cantacessi, Cantacessi, Cantacessi, Chan, Chang, Cinzia Cantacessi, Clifton, Conesa, Cottee, Cottee, Datu, DeRisi, Doyle, Flicek, Freigofas, Gasser, Golden, Greene, Gupta, Hawdon, Hopkins, Hotez, Hu, Huang, Hunter, Iseli, Jackson, Joachim, Joachim, Keil, Krasky, Letunic, Li, Li, Li, Lipinski, Makedonka Mitreva, Margulies, Matthew J. Nolan, McKay, Metzker, Miller, Miller, Mizuarai, Moreno, Morozova, Moser, Mufson, Mulvenna, Nagaraj, Nagaraj, Neil D. Young, Nikolaou, Nisbet, Olson, Parkinson, Paul W. Sternberg, Pong, Portman, Ranganathan, Ren, Robertson, Robin B. Gasser, Robinson, Ross S. Hall, Sahar Abubucker, Sanger, Sanger, Santos, Shoba Ranganathan, Soderlund, Stathopoulos, Stockdale, Tanaka, Vibranovski, Wang, Williamson, Wilson, Wu, Young, Young, Zhan, Zhong   +95 more
core   +6 more sources

An extracellular matrix-related prognostic and predictive indicator for early-stage non-small cell lung cancer

Nature Communications, 2017
Prognosis and prediction of adjuvant chemotherapy response in non-small cell lung cancer can have significant clinical impact. Here, the authors show that differential expression of a 29 extracellular matrix gene indicator, EPPI, can predict patient ...
Su Bin LIM, Swee Jin TAN, Wan-Teck LIM, Chwee Teck LIM   +3 more
doaj   +1 more source

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]

, 2017
Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S, Brockman, Scott, Chinnaiyan, Arul M, Chugh, Rashmi, Feng, Felix Y, Grasso, Catherine S, Gursky, Amy, Haakenson, Christine, Henderson, James, Herman, Kirk, Hovelson, Daniel H, Husain, Hatim, Hussain, Maha H, Kamberov, Emmanuel, Kandarpa, Malathi, Kang, Qing, Krauss, John C, Langmore, John, Liu, Chia-Jen, Lonigro, Robert J, Mills, Ryan E, Morgan, Todd M, Quist, Michael J, Ramnath, Nithya, Robinson, Dan, Smith, David C, Talpaz, Moshe, Tesmer, Tim, Tewari, Muneesh, Tomlins, Scott A, Tuck, Missy, Wang, Yugang   +31 more
core   +1 more source

Assessing Transaction Environment Conditions for Investment and Construction

MATEC Web of Conferences, 2016
This paper contains characteristic description of the transaction-based approach and identifies problems of studying the transaction envi-ronment for investments and construction.
Mishlanova Marina, Kharitonov Vadim
doaj   +1 more source

Clonal Analysis Delineates Transcriptional Programs of Osteogenic and Adipogenic Lineages of Adult Mouse Skeletal Progenitors

Stem Cell Reports, 2018
Summary: Bone, cartilage, and marrow adipocytes are generated by skeletal progenitors, but the relationships between lineages and mechanisms controlling their differentiation are poorly understood.
Maria Rostovskaya, Samantha Donsante, Benedetto Sacchetti, Dimitra Alexopoulou, Sylvia Klemroth, Andreas Dahl, Mara Riminucci, Paolo Bianco, Konstantinos Anastassiadis   +8 more
doaj   +1 more source