Results 51 to 60 of about 382,279 (282)

Genetic sampling for estimating density of common species. [PDF]

open access: yes, 2017
Understanding population dynamics requires reliable estimates of population density, yet this basic information is often surprisingly difficult to obtain.
Cheng, Ellen   +3 more
core  

Sky coverage modeling for the whole sky for laser guide star multiconjugate adaptive optics [PDF]

open access: yes, 2012
The scientific productivity of laser guide star adaptive optics systems strongly depends on the sky coverage, which describes the probability of finding natural guide stars for the tip/tilt wavefront sensor(s) to achieve a certain performance.
Andersen, David   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

From Sequence to Solution: Intelligent Learning Engine Optimization in Drug Discovery and Protein Analysis

open access: yesBioTech
This study introduces the intelligent learning engine (ILE) optimization technology, a novel approach designed to revolutionize screening processes in bioinformatics, cheminformatics, and a range of other scientific fields.
Jamal Raiyn   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Application of Next-Generation Sequencing Technology in Southeast Asia: A Practical Framework for Advancing Wildlife Conservation [PDF]

open access: yesBIO Web of Conferences
Next-generation sequencing (NGS) has transformed genomics, presenting significant potential for advancing wildlife conservation. NGS technology offers opportunities and challenges for addressing scientific questions in wildlife management. Unfortunately,
Othman Nursyuhada   +11 more
doaj   +1 more source

NGS y Metagenómica [PDF]

open access: yes, 2016
The Next Generation Sequencing (NGS) allows to sequence the whole genome of an organism, compared to Maxam and Gilbert and Sanger sequencing that only allow to sequence, hardly, a single gene.
Alba-Bernal, Alfonso   +1 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Soil microbial load modulation improves plant–microbe interactions and bioinoculant efficacy in pathogen-stressed soils

open access: yesFrontiers in Plant Science
Plants establish a close association with a community of microbes naturally living in the soil, known as resident soil microbiome, which typically maintains a dynamic equilibrium that confers resilience against biotic and abiotic perturbations.
Yohannes Ebabuye Andargie   +12 more
doaj   +1 more source

Application of Next-Generation Sequencing in Infections After Allogeneic Haematopoietic Stem Cell Transplantation: A Retrospective Study

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
This retrospective study aimed to determine the characteristics of infection and diagnostic efficacy of next-generation sequencing (NGS) in patients with fever after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Xiaoying Zhang   +6 more
doaj   +1 more source

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