Results 121 to 130 of about 175,969 (264)

Next Generation Sequencing for the Differentiation of Benign and Malignant Biliary Strictures. [PDF]

Liver Int
Gillmeister A, Husman J, Schmelz R, Brückner S, Hampe J, Aust D, Zeissig S.   +6 more
europepmc   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Glioblastoma recurrence: An NGS-centered seed-soil framework. [PDF]

Neoplasia
Xu JY, Chen J, Feng W, Yi GZ.
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

High-Sensitivity ctDNA Analysis Uncovers Relevant Signals Missed by NGS in Pancreatic Cancer. [PDF]

Clin Cancer Res
Sridalla K, Machhi JK, Vitello DJ, Chibucos A, Cox M, Wells A, Horowitz A, Rengaraju V, Shen C, Romero N, Temosihue I, Janczewski LM, Abad J, Dawravoo K, Bentrem D, Jennings LJ, Zhang Q, Chawla A.   +17 more
europepmc   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Measurable residual disease detected by next-generation sequencing in T-cell acute lymphoblastic leukemia. [PDF]

Nat Commun
Liao C, Chen H, Xu L, Lin S, Zhang J, Xu W, Liang J, Zhao F, Shen D, Shen H, Song H, Tang Y, Xu X.   +12 more
europepmc   +1 more source

Kompilasyon Ng Talaan Ng Mga Guro Na Nagtamo Ng Titulong Master Kaugnay Ng Kanilang Promosyon Sa Lalawigan Ng Sorsogon

Sinuri ng pag-aaral na ito ang epekto ng pagtatamo ng Master’s degree sa pagganap sa pagtuturo at promosyon ng mga guro sa Junior High School sa lalawigan ng Sorsogon. Gamit ang disenyong quantitative descriptive at total enumeration sa 100 guro mula sa siyam na pampublikong paaralang sekondarya, natuklasan na ang mga guro ay may mataas na antas ng ...
openaire   +2 more sources

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source