Results 121 to 130 of about 386,400 (307)

Sam2bam: High-Performance Framework for NGS Data Preprocessing Tools

open access: yes, 2016
This paper introduces a high-throughput software tool framework called {\it sam2bam} that enables users to significantly speedup pre-processing for next-generation sequencing data.
Cheng, Yinhe   +2 more
core   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Missense mutations of NCPAG gene affect calving ease in Piedmontese cattle: preliminary evidences

open access: yesItalian Journal of Animal Science, 2018
A previous genome scan on 323 Piedmontese individuals identified a cluster of 13 SNPs significantly associated with direct calving ease and centred on the three genes LAP3, LCORL and NCAPG in chromosome 6.
Giovanni Chillemi   +7 more
doaj   +1 more source

Genome-wide patterns of polymorphism in an inbred line of the African malaria mosquito Anopheles gambiae. [PDF]

open access: yes, 2014
Anopheles gambiae is a major mosquito vector of malaria in Africa. Although increased use of insecticide-based vector control tools has decreased malaria transmission, elimination is likely to require novel genetic control strategies.
Gamez, Stephanie   +2 more
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Detectarea și analiza mutațiilor somatice în unele probe de adenocarcinom pulmonar prin tehnologia de secvențiere ION TORRENT.

open access: yesBuletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019
Cancerul pulmonar este cea mai comună cauză a mortalității prin cancer și cel mai comun cancer din lume cu peste 1,5 milioane de decese anual. Explorarea aspectelor genomice, studiul profilului molecular și selectarea terapiilor țintite pentru aceste ...
Valentina Stratan   +8 more
doaj  

Bethe-Ansatz density-functional theory of ultracold repulsive fermions in one-dimensional optical lattices

open access: yes, 2005
We present an extensive numerical study of ground-state properties of confined repulsively interacting fermions on one-dimensional optical lattices.
A. Griffin   +21 more
core   +1 more source

Lawak ng Pagkatuto ng Mag-aaral Kaugnay saPaggamit ng Differentiated Instruksyon

open access: yes, 2020
Ang pag-aaral na ito ay pagsusuri sa lawak ng pagkatuto ng mga mag-aaral kaugnay sa paggamit ng Differentiated instruksyon. Ang mga respondent ng pananaliksik na ito ay ang piling mga mag-aaral at mga guro na kasalukuyang nagtuturong asignaturang Filipino na gumamit ng differentiated instruksyon sa kanilang pagtuturo.
openaire   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Recovery of Dysregulated Genes in Cancer-Related Lower Limb Lymphedema After Supermicrosurgical Lymphaticovenous Anastomosis – A Prospective Longitudinal Cohort Study

open access: yesJournal of Inflammation Research, 2022
Johnson Chia-Shen Yang,1,2 Lien-Hung Huang,1,2 Shao-Chun Wu,3,4 Yi-Chan Wu,1,4 Chia-Jung Wu,1,4 Chia-Wei Lin,1,4 Pei-Yu Tsai,1,4 Peng-Chen Chien,1,4 Ching-Hua Hsieh1,2 1Division of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung ...
Yang JCS   +8 more
doaj  

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