Results 141 to 150 of about 169,956 (263)

Application of Newly Customized Myeloid NGS Panel in the Diagnosis of Myeloid Malignancies

International Journal of General Medicine
Heba A Alkhatabi,1,2 Wejdan Alqahtani,3 Reem Alsolami,1,2 Aisha Elaimi,1,4 Mohannad S Hazzazi,1,2 Majed N Almashjary,1,2 Hind A Alkhatabi,5 Mohammad E Alghuthami,6 Yara M Daous,2,7 Elrashed B Yasin,8 Ahmed Barefah2,9 1Department of Medical Laboratory ...
Alkhatabi HA, Alqahtani W, Alsolami R, Elaimi A, Hazzazi MS, Almashjary MN, Alkhatabi HA, Alghuthami ME, Daous YM, Yasin EB, Barefah A   +10 more
doaj  

Sonogenetic flexible nanogels enabling enhanced calcium overload-induced immunogenic cell death for tumor immunotherapy. [PDF]

Bioact Mater
Han B, Dai Z, Liu Q, Li X, Jia F, Deng X, Tian R, Ning M, Chen H.   +8 more
europepmc   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

A saddle-shaped OBO-doped nanographene: facile synthesis, adaptive double-layer assembly, and enhanced Lewis acidity. [PDF]

Chem Sci
Zhang K, Chen ZC, Jia S, Yao YR, Tian HR, Deng QS, Wu XM, Li J, Deng SL, Xie SY, Zhang Q.   +10 more
europepmc   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Minimally invasive characterization of peripheral blood measurable residual disease in multiple myeloma using high-sensitivity detection of ctDNA by next-generation sequencing. [PDF]

Hemasphere
Buenache N, Lasa M, Arroyo A, González C, Haertle L, Ruiz-Heredia Y, Ayala R, Alonso R, Martín-Muñoz A, Rosa-Rosa JM, González V, Calasanz MJ, Rodríguez-Otero P, Rosiñol L, De Arriba F, Ocio EM, Oriol A, González Y, Sureda A, Lakhwani S, Clavero ME, Ibáñez A, Gómez C, Orfao A, Mateos MV, Lahuerta JJ, Cedena MT, Bladé J, San Miguel J, Puig N, Paiva B, Martínez-López J.   +31 more
europepmc   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Electric field-guided random-access DNA data storage. [PDF]

Sci Adv
Lim D, Kang T, Lee W, Haider Z, Noh S, Yu M, Huang X, Eun HS, Song Y.   +8 more
europepmc   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Coordination-based nanocomposite hydrogel promotes tissue regeneration under infection-compromised conditions. [PDF]

Regen Biomater
Yu K, Zhong J, Ma Y, Li J, Wei Y, Zheng H, Li F, Jiang L.   +7 more
europepmc   +1 more source