Results 21 to 30 of about 7,650 (179)

A split-face study to evaluate the efficacy of a dissolving microneedle-encapsulated niacinamide skin patch for the reduction of facial hyperpigmentation [PDF]

Archives of Aesthetic Plastic Surgery, 2022
Background This study aimed to evaluate the efficacy and safety of a dissolving microneedle (DMN)-encapsulated niacinamide skin patch to reduce facial hyperpigmentation.
Joon Suk Bae, Seung Min Nam, Han Gyu Cha, Eun Soo Park   +3 more
doaj   +1 more source

Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

Antioxidants, 2020
The potential of nicotinamide (NAM) to prevent atherosclerosis has not yet been examined. This study investigated the effect of NAM supplementation on the development of atherosclerosis in a mouse model of the disease.
Karen Alejandra Méndez-Lara, Nicole Letelier, Núria Farré, Elena M. G. Diarte-Añazco, Núria Nieto-Nicolau, Elisabeth Rodríguez-Millán, David Santos, Victor Pallarès, Joan Carles Escolà-Gil, Tania Vázquez del Olmo, Enrique Lerma, Mercedes Camacho, Ricardo P Casaroli-Marano, Annabel F. Valledor, Francisco Blanco-Vaca, Josep Julve   +15 more
doaj   +1 more source

Anti-Aging and Lightening Effects of Au-Decorated Zeolite-Based Biocompatible Nanocomposites in Epidermal Delivery Systems

Journal of Functional Biomaterials, 2023
The main challenges in developing zeolites as cosmetic drug delivery systems are their cytotoxicities and the formation of drug-loading pore structures.
Seungyeon Lee, Geunjeong Lee, Giyoung Jeon, Hayeong Lee, Suhyeon Park, Youngju Sohn, Youngkum Park, Seongwoo Ryu   +7 more
doaj   +1 more source

Evaluation of Sebostatic Activity of Juniperus communis Fruit Oil and Pelargonium graveolens Oil Compared to Niacinamide

Cosmetics, 2017
As a facial skin condition, oily skin causes cosmetic problems, such as large pores, shiny appearance, and the feeling of greasiness and heaviness. Furthermore, extensive sebum production leads to common skin disorders such as acne vulgaris or seborrheic
Justyna Kozlowska, Anna Kaczmarkiewicz, Natalia Stachowiak, Alina Sionkowska   +3 more
doaj   +1 more source

Topical delivery of niacinamide: Influence of neat solvents [PDF]

International Journal of Pharmaceutics, 2020
Niacinamide (NIA) has been widely used in cosmetic and personal care formulations for several skin conditions. Permeation of topical NIA has been confirmed in a number of studies under infinite dose conditions. However, there is limited information in the literature regarding permeation of NIA following application of topical formulations in amounts ...
Iliopoulos, F, Sil, B, Al-Hossain, ASMM, Moore, D, Lucas, R, Lane, M   +5 more
openaire   +5 more sources

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

A Mixture of Topical Forms of Polydeoxyribonucleotide, Vitamin C, and Niacinamide Attenuated Skin Pigmentation and Increased Skin Elasticity by Modulating Nuclear Factor Erythroid 2-like 2

Molecules, 2022
It is well-known that increased oxidative stress caused by ultraviolet B (UV-B) radiation induces melanogenesis and activates metalloproteinases (MMPs), which degrade collagen and elastin fibers, leading to decreased skin elasticity.
Hyoung Moon Kim, Kyung-A Byun, Seyeon Oh, Jin Young Yang, Hyun Jun Park, Moon Suk Chung, Kuk Hui Son, Kyunghee Byun   +7 more
doaj   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Assessment of the feed additive consisting of niacinamide for all animal species for the renewal of its authorisation (Arxada Ltd)

EFSA Journal, 2023
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of niacinamide as a nutritional additive for use in all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Luca Tosti, Orsolya Holczknecht, Matteo Lorenzo Innocenti, Paola Manini, Maria Vittoria Vettori, Fabiola Pizzo   +23 more
doaj   +1 more source

Biopolymer- and Natural Fiber-Based Biomimetic Tissues to Realize Smart Cosmeceuticals and Nutraceuticals Using an Innovative Approach

Pharmaceutics, 2023
More sustainable and smart cosmeceuticals and nutraceuticals are necessary due to the ecological transition. In this study, a pullulan-based water solution containing chitin nanofibril–nano-lignin (CN-LG) complexes that encapsulate fish collagen ...
Pierfrancesco Morganti, Maria-Beatrice Coltelli, Alessandro Gagliardini, Andrea Lazzeri, Gianluca Morganti, Giovanna Simonetti, Tilman Fritsch, Vittorio Calabrese, Alessandra Fusco, Giovanna Donnarumma   +9 more
doaj   +1 more source