Results 251 to 260 of about 286,454 (285)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Arterial Enhancement Fraction-Spectral CT-Based Model as Part of Prediction Model in BRAF^V600E-Positive Papillary Thyroid Carcinoma. [PDF]

Diagnostics (Basel)
Zhou B, Lv L, Zou Y, Song Z, Yu J, Zhang X, Zhang D.   +6 more
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Sustaining Health Promotion and Education to Build Resilient Communities: Lessons from Nurses During the COVID-19 Pandemic. [PDF]

Int J Environ Res Public Health
Ohene LA, Iddrisu M, Aziato L.
europepmc   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Taxonomic novelties and phylogenetic insights on Gilliesieae (Allioideae, Amaryllidaceae) from Chile. [PDF]

PhytoKeys
García N, Zúñiga-Acevedo P, González MA, Espinoza MM, Soto C, Cisternas-Gallardo BJ.   +5 more
europepmc   +1 more source

A supramolecular semiconducting nickel(ii)-metallohydrogel with dual antimicrobial and micro-electronic device applications. [PDF]

RSC Adv
Dhibar S, Mohan A, Laha R, Some S, Kaith P, Trivedi A, Bhattacharjee S, Nthunya LN, Ajiboye TO, Bera A, Panja SK, Das AK, Dam S, Predeep P, Saha B.   +14 more
europepmc   +1 more source

Selective Effects of Acutely Administered N-Acetyl-Cysteine in Rodent Models of Nicotine-Conditioned Behaviours. [PDF]

Addict Biol
Stoddart K, Davies M, Oughton J, Malcolm E, AlSharari SD, Shoaib M.   +5 more
europepmc   +1 more source

Dapagliflozin attenuates nicotine-induced apoptosis by targeting the ASK1/p38/JNK apoptotic pathway in HK-2 cells. [PDF]

Sci Prog
Li SY, Cui S, Nan QY, Lin XJ, Zheng HL, Piao SG, Jin JZ, Chung BH, Yang CW, Wang L, Li C.   +10 more
europepmc   +1 more source