Placental transfer of intravenous nicardipine and disposition into breast milk during the control of hypertension in women with pre-eclampsia [PDF]
, 2016 埼玉医科大学平成25年
松村 英祥
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Pharmacologic Management of Pediatric Hypertension [PDF]
, 2015 Hypertension in children is common, and the prevalence of primary hypertension is increasing with the obesity epidemic and changing dietary choices. Careful measurement of blood pressure is important to correctly diagnose hypertension, as many factors ...
Misurac, Jason +2 more
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Interstitial cell network volume is reduced in the terminal bowel of ageing mice [PDF]
, 2018 Ageing is associated with impaired neuromuscular function of the terminal gastrointestinal (GI) tract, which can result in chronic constipation, faecal impaction and incontinence.
Gamage, Prasanna P. K. M. +4 more
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Collateral and collateral-adjacent hyperemic vascular resistance changes and the ipsilateral coronary flow reserve: Documentation of a mechanism causing coronary steal in patients with coronary artery disease [PDF]
, 2017 Objectives: The goal of this clinical study was to assess the influence of hyperemic ipsilateral, collateral and contralateral vascular resistance changes on the coronary flow velocity reserve (CFVR) of the collateral-receiving (i.e. ipsilateral) artery,
Billinger, Michael +4 more
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A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI [PDF]
, 2013 BACKGROUND: Acute kidney injury (AKI) is a frequent condition in hospitalised patients undergoing major surgery or the critically ill and is associated with increased mortality.
Delles, C. +6 more
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Not only P-glycoprotein: amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins [PDF]
, 2017 The development of drug resistance continues to be a dominant hindrance toward curative cancer treatment. Overexpression of a wide-spectrum of ATP-dependent efflux pumps, and in particular of ABCB1 (P-glycoprotein or MDR1) is a well-known resistance ...
Assaraf, Yehuda G. +4 more
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Western Journal of Emergency Medicine, 2015 Introduction: Hypertensive emergency has a high mortality risk and the treatment goal is to quickly lower blood pressure with intravenous (IV) medications.
Freiermuth, Caroline E. +2 more
doaj +1 more source
Store-operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells. [PDF]
, 2016 KEY POINTS: Depletion of Ca(2+) stores activates store-operated channels (SOCs), which mediate Ca(2+) entry pathways that regulate cellular processes such as contraction, proliferation and gene expression.
Albert, AP +4 more
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Physiology-Aware Rural Ambulance Routing
, 2017 In emergency patient transport from rural medical facility to center tertiary hospital, real-time monitoring of the patient in the ambulance by a physician expert at the tertiary center is crucial.
Berlin Jr., Richard B. +2 more
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Controlled release floating multiparticulates of metoprolol succinate by hot melt extrusion [PDF]
, 2015 YesWe present hot melt extrusion (HME) for the design of floating multiparticulates. Metoprolol succinate was selected as the model drug. Our foremost objective was to optimize the components Eudragit® RS PO, polyethylene oxide (PEO) and hydroxypropyl ...
Devarajan, P.V. +2 more
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