Results 101 to 110 of about 15,118 (218)

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

open access: yes
The Journal of Dermatology, Volume 52, Issue 6, Page e430-e480, June 2025.
Yoshihide Asano   +27 more
wiley   +1 more source

Optimization of a sensitive and reliable UPLC-MS/MS method to simultaneously quantify almonertinib and HAS-719 and its application to study the interaction with nicardipine

open access: yesPharmaceutical Biology
Context Almonertinib is primarily metabolized by CYP3A4, so it could interact with a variety of drugs metabolized by CYP3A4, leading to the changes of systemic exposure.Objective For the purpose of this experiment, an ultra-performance liquid ...
Dongxin Chen   +6 more
doaj   +1 more source

NG-Nitro-L-arginine Methyl Ester-Induced Potentiaton of the Effect of Aminophylline on Rat Diaphragm: the Role of Extracellular Calcium

open access: yesJournal of Pharmacological Sciences, 2004
The role of extracellular calcium in the interaction between intracellular cAMP and nitric oxide (NO)/cGMP on the contractility of rat diaphragm pretreated with cumulative concentrations of aminophylline (0.36 – 3.60 mM) was investigated.
Radan Stojanović   +5 more
doaj   +1 more source

High-performance liquid chromatographic method for the determination of nicardipine in pure, pharmaceutical preparations and plasma and its application to pharmacokinetics in humans

open access: yesOrbital: The Electronic Journal of Chemistry, 2009
A simple, sensitive and reproducible reversed-phase liquid chromatographic method has been developed and validated for the determination of nicardipine hydrochloride (NC) in pure, pharmaceutical preparations, human plasma and the study of the ...
Sheikha M. Al-Ghannam, Abeer M. Al-Olyan
doaj  

Physiologically Based Pharmacokinetic (PBPK) Modeling to Predict CYP3A-Mediated Drug Interaction between Saxagliptin and Nicardipine: Bridging Rat-to-Human Extrapolation

open access: yesPharmaceutics
The aim of this study was to predict the cytochrome P450 3A (CYP3A)-mediated drug–drug interactions (DDIs) between saxagliptin and nicardipine using a physiologically based pharmacokinetic (PBPK) model.
Jeong-Min Lee   +3 more
doaj   +1 more source

Development of Immobilised Biopolymer Stationary Phases based on the Efflux Transporters [PDF]

open access: yes
The body is continuously exposed to a variety of toxins and metabolic waste products but is able to rid itself of these by using various detoxification mechanisms such as enzymes and transmembrane transporters.
Patel, Sharvil Pankaj
core  

Safety and Tolerability of Concentrated Intraventricular Nicardipine for Poor-Grade Aneurysmal Subarachnoid Hemorrhage–Related Vasospasm [PDF]

open access: gold, 2023
Kaneez Zahra   +8 more
openalex   +1 more source

Comparison of the effects of nicardipine and remifentanil on surgical visual field and hemodynamic parameters in tympanomastoidectomy cases

open access: yesMedicine Science
In this study; We aimed to compare the surgical visual field and hemodynamic effects of Nicardipine and Remifentanil in microscopic tympanomastoidectomy patients. The study was planned as a prospective, double-blind, and randomized clinical trial.
Celal Saritoy   +4 more
doaj   +1 more source

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