Results 11 to 20 of about 15,118 (218)

Potential anaphylactoid reaction to nicardipine [PDF]

Journal of the American College of Emergency Physicians Open
Anaphylactic and anaphylactoid reactions are both acute allergic responses known to be potentially fatal if not treated emergently. Signs include bronchospasm, urticaria, nausea and vomiting, pharyngeal edema and cardiovascular collapse.
Ali M. Hassan, Holli Hill, Chad Donley, Carmen Leonelli   +3 more
doaj   +2 more sources

Repurposing nicardipine leads to improved development in a young patient with Pitt–Hopkins syndrome [PDF]

Frontiers in Pharmacology
We describe a drug repurposing treatment involving the use of nicardipine in a young patient with Pitt-Hopkins syndrome (a rare neurodevelopmental disorder that results from variants of TCF4 gene) as a bench-to-bedside approach.
Marta Agnes Somorai, Marta Agnes Somorai, Marta Agnes Somorai, Sean Ekins, Claudia Rupprecht, Clara Lettl, Volker Mall, Volker Mall, Volker Mall   +8 more
doaj   +2 more sources

Effects of intrathecal administration of sodium nitroprusside and nicardipine on cerebral pial microcirculation, cortical tissue oxygenation, and electrocortical activity in the early post-resuscitation period in a porcine cardiac arrest model. [PDF]

PLoS ONE
Recent studies suggested intrathecal vasodilator administration as a therapy to mitigate post-ischemic cerebral hypoperfusion following cardiac arrest. We examined the effects of two commonly used intrathecal vasodilators, sodium nitroprusside (SNP) and ...
Hyoung Youn Lee, Najmiddin Mamadjonov, Kyung Woon Jeung, Yong Hun Jung, Wan Young Heo, Yong Soo Cho, Byung Kook Lee, Tag Heo   +7 more
doaj   +2 more sources

Comparison of Esmolol and Nicardipine treatment in hypertensive acute ıschemic stroke patients [PDF]

Scientific Reports
The most important risk factor in ischaemic stroke patients is hypertension (HT). Blood pressure regulation has an important role in hypertensive acute ischaemic stroke patients (AIS).
Adem Melekoğlu, Uğur Kahveci, Zeynep Köksal, Serkan Ceritli, Ertuğrul Altınbilek, Miray Korkmaz   +5 more
doaj   +2 more sources

A PBPK modeling approach for personalized dose optimization of nicardipine in renal and hepatic dysfunction [PDF]

Scientific Reports
Nicardipine is a calcium channel blocker employed to manage hypertension and angina. It is primarily metabolized in the liver; therefore, hepatic impairment patients may experience drug accumulation, potentially resulting in adverse events. This research
Ammara Ayub, Ammara Zamir, Muhammad Fawad Rasool, Usman Arshad, Faleh Alqahtani   +4 more
doaj   +2 more sources

The Clinical Research Landscape of Intracranial Nicardipine for Aneurysmal Subarachnoid Hemorrhage: Insights From Bibliometric Analysis [PDF]

Drug Design, Development and Therapy
Guangtang Chen,1,* Yi Cao,1,2,* Xiaolin Du,3,* Junshuan Cui,1 Xi Zeng,1 Hua Yang,1 Zeguang Ren,1 Kaya Xu1 1Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China; 2School of ...
Chen G, Cao Y, Du X, Cui J, Zeng X, Yang H, Ren Z, Xu K   +7 more
doaj   +1 more source

The effect of dexmedetomidine compound nicardipine in transnasal endoscopic pituitary tumor resection [PDF]

BIO Web of Conferences, 2022
Objective: To compare the effect of dexmedetodeidine and nicardipine alone in transnasal endoscopic pituitary tumor resection, and to find a more suitable controlled antihypertensive regimen.
Yang Xin
doaj   +1 more source

Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT A recent survey in the Philippines, PRESYON‐4, showed increasing prevalence of hypertension from 22% in the 1990s to 37% in 2021, of which only 52% were aware of their diagnosis. While rates of treatment and adherence were 68% and 86%, respectively, the rate of BP control was low at 37%. Furthermore, there remained a high degree of unawareness
Ona D, Punzalan F, Oliva R, Sucaldito M, Espallardo N, Santos R, Almenario H, Murillo K, Dones V, Llanes E, Santos L, Jose M, Fusingan‐Peralta A, Bataclan R, Mata M, Convocar P, Leus A, Vilela G.   +17 more
europepmc   +2 more sources

Nicardipine Inhibits Breast Cancer Migration via Nrf2/HO-1 Axis and Matrix Metalloproteinase-9 Regulation

Frontiers in Pharmacology, 2021
Background: Metastasis represents an advanced stage of cancers, and matrix metalloproteinases are critical regulators. Calcium signal is crucial for appropriate cell behaviors.
Yen-Chang Chen, Yen-Chang Chen, Jia-Hong Chen, Cheng-Fang Tsai, Chen-Teng Wu, Miao-Hsiang Wu, Pei-Chun Chang, Wei-Lan Yeh, Wei-Lan Yeh, Wei-Lan Yeh   +9 more
doaj   +1 more source

Gasserian ganglion radiofrequency thermoablation in a patient with aneurysm of the anterior communicating artery -A case report- [PDF]

Anesthesia and Pain Medicine, 2021
Background Gasserian ganglion radiofrequency thermoablation is a good treatment option for the management of pain in trigeminal neuralgia. We report a case in which the patient of trigeminal neuralgia combined with anterior cerebral artery aneurysm was ...
Yong Ho Lee, Ji Hee Hong, Hye Kyung Shin
doaj   +1 more source