Results 21 to 30 of about 15,118 (218)

Safety and efficacy of intrathecal nicardipine for aneurysmal subarachnoid hemorrhage induced vasospasm

Interdisciplinary Neurosurgery, 2021
Background: Cerebral vasospasm (CV) is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) and is associated with significant morbidity and mortality.
Jonathan M. Parish, Robert Ziechmann, Natalie M. Guley, Jeremy Joy, Brandon Karimian, E. Hunter Dyer, Scott D. Wait, William R. Stetler, Joe D. Bernard   +8 more
doaj   +1 more source

Development of an Oral Liquid Formulation of Nicardipine Hydrochloride Compounded with Simple Excipients for the Treatment of Pediatric Hypertension

Pharmaceutics, 2023
Nicardipine hydrochloride is an anti-hypertensive drug that is used off-label to treat hypertension in children. A previous oral formulation of nicardipine hydrochloride was developed using a commercial vehicle as an excipient.
Marine Cavelier, Henri Gondé, Damien Costa, Fabien Lamoureux, Tony Pereira, Nimrod Buchbinder, Rémi Varin, Charles Hervouët   +7 more
doaj   +1 more source

The calcium channel blocker Cav2.1 combined with amyloid beta monoclonal antibodies may reduce the occurrence of ARIA‐E [PDF]

Alzheimers Dement
Abstract Background Amyloid‐targeting monoclonal antibodies were approved by FDA in the treatment of Alzheimer’s disease, some patients have experienced adverse reactions related to amyloid‐associated imaging abnormalities, including both cerebral edema‐type(ARIA‐E) and cerebral hemorrhage‐type(ARIA‐H), which significantly impact the overall prognosis ...
An D, Li X, Xu Y.
europepmc   +2 more sources

A randomized controlled trial comparing blood pressure reduction in hyperacute phase of spontaneous intracerebral hemorrhage by continuous nicardipine infusion with or without a preceding nicardipine bolus dose

Heliyon, 2023
Objectives: To determine whether addition of an intravenous bolus dose before continuous nicardipine infusion would improve blood pressure reduction in the hyperacute phase in patients with spontaneous intracerebral hemorrhage (ICH). Design: Double-blind
Adisak Nithimathachoke, Supatpinee Tiensawang, Natradee Deechot, Chawin Sutaparak, Kitiporn Sriamornrattanakul   +4 more
doaj   +1 more source

The effect of nicardipine on the zone of stasis in burns: An experimental rat model. [PDF]

Ulus Travma Acil Cerrahi Derg
Deniz R, İğde M, Tan Başer N, Atılgan N, Yumuşak N, Birtane N, Zan U.   +6 more
europepmc   +3 more sources

Changes in Mean Arterial and Blood Pressure in Using Nicardipine in Hypertensive Crisis Patients at the Hajj General Hospital Surabaya from August to December 2021

Borneo Journal of Pharmacy, 2023
Hypertension crisis is one of the most common disease problems; it will cause complications and death. Therapeutic management guidelines that the calcium channel blocker group, one of which is nicardipine, can increase the achievement of goals in mean ...
Selly Septi Fandinata, Rizky Darmawan, Ninik Mas Ulfa, Deddy Aryanda Putra   +3 more
doaj   +1 more source

Nicardipine for Hypertension following Aortic Coarctectomy and Superior Cavopulmonary Anastomosis [PDF]

, 2015
Background: Literature on the use of nicardipine, a dihydropyridine calcium channel antagonist, in children recovering from cardiac surgery is sparse and, to our knowledge, nonexistent in children with single ventricle anatomy.
Mastropietro, Christopher W., Uribe, Diego Arango   +1 more
core   +1 more source

Identification of a rhythmic firing pattern in the enteric nervous system that generates rhythmic electrical activity in smooth muscle [PDF]

, 2018
The enteric nervous system (ENS) contains millions of neurons essential for organization of motor behavior of the intestine. It is well established that the large intestine requires ENS activity to drive propulsive motor behaviors.
Brookes, Simon J, Costa, Marcello, Dinning, Phil G, Hibberd, Timothy J, Hu, Hongzhen, Keating, Damien J, Sorensen, Julian, Spencer, Nick J, Travis, Lee, Wattchow, David A, Wiklendt, Lukasz   +10 more
core   +2 more sources

Does a single dose of intravenous nicardipine or nimodipine affect the bispectral index following rapid sequence intubation? [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundTheoretically, L-type calcium channel blockers could modulate anesthetic effects. Nicardipine does not affect the bispectral index (BIS), but nimodipine, which can penetrate the blood-brain barrier, has not been studied.
Jeong Jin Lee, Jie Ae Kim, Hyun Joo Ahn, Jin-Kyoung Kim, Mikyung Yang, Soo Joo Choi, Hyun-Soo Kim, Soo Hyun Yang   +7 more
doaj   +1 more source

Intravenous nicardipine and labetalol use in hypertensive patients with signs or symptoms suggestive of end-organ damage in the emergency department: a subgroup analysis of the CLUE trial

BMJ Open, 2013
Objective To compare the efficacy of Food and Drug Administration recommended dosing of nicardipine versus labetalol for the management of hypertensive patients with signs and/or symptoms (S/S) suggestive of end-organ damage (EOD).Design Secondary ...
Brian Hiestand, Phillip Levy, W Frank Peacock, Brigitte M Baumann, Richard M Nowak, Amy Hsu, Joseph Varon, Chad M Cannon, David M Cline, Pierre Borczuk, Abhinav Chandra, Deborah B Diercks, Preeti Jois, Brian Kaminski, Jon W Schrock   +14 more
doaj   +1 more source