Results 51 to 60 of about 15,118 (218)

Latent stem and progenitor cells in the hippocampus are activated by neural excitation [PDF]

, 2008
The regulated production of neurons in the hippocampus throughout life underpins important brain functions such as learning and memory. Surprisingly, however, studies have so far failed to identify a resident hippocampal stem cell capable of providing ...
Bartlett, Perry F., Black, Debra M., Sah, Pankaj, Walker, Tara L., Wallace, Robyn H., White, Amanda   +5 more
core   +1 more source

Clevidipine for Perioperative Blood Pressure Control in Infants and Children

Pharmaceuticals, 2013
Various pharmacologic agents have been used for perioperative BP control in pediatric patients, including sodium nitroprusside, nitroglycerin, β-adrenergic antagonists, fenoldopam, and calcium channel antagonists. Of the calcium antagonists, the
Sergio D. Bergese, David B. Tulman, Joseph D. Tobias   +2 more
doaj   +1 more source

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 198-207, January 2026.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Edible Seeds in the Fight Against Hypertension: A Review of In Vitro, In Vivo, and Clinical Evidences With a Mechanistic Insight of Bioactive Compounds

Food Frontiers, Volume 7, Issue 1, January 2026.
The presented review provides the potential antihypertensive benefits of traditionally employed edible seeds, presenting new perspectives and avenues for future research. ABSTRACT Hypertension, often referred to as a silent killer, is responsible for 7.5 million deaths, representing approximately 12.8% of all global mortality.
Jinmin Shi, Mohamad Fawzi Mahomoodally, Ahmed Abduljalal Abduljabbar, Ruttun Bushra Umme Zainab, Katharigatta N. Venugopala, Gokhan Zengin, Sakina Yagi, Meng‐Yao Li, Xuebo Hu   +8 more
wiley   +1 more source

Bioequivalence Study of Nicardipine Solution Versus Nicardipine Tablets

Clinical and Experimental Hypertension, 2004
The bioequivalence of a solution (investigational product) and a tablet (reference product) formulation of the dihydropyridine-type derivative Ca2+ antagonist nicardipine were investigated by measuring plasma levels of the compound after single randomized administration of 20 mg of the two formulations.
MIGNINI F, BISBOCCI, Daniela, PAGLIERI C, STRECCIONI V, VEGLIO, Franco, AMENTA F.   +5 more
openaire   +4 more sources

Chronic beta-adrenoceptor blockade and human atrial cell electrophysiology: evidence of pharmacological remodelling [PDF]

, 2003
<b>Objective:</b> Chronic beta-adrenoceptor antagonist (β-blocker) treatment reduces the incidence of reversion to AF in patients, possibly via an adaptive myocardial response.
Kane, K.A., Norrie, J., Rankin, A.C., Russell, J.A., Workman, A.J.   +4 more
core   +1 more source

Nicardipine‐induced acute respiratory failure: Case report and literature review

Clinical Case Reports, 2023
Hypoxic pulmonary vasoconstriction (HPV) is a major physiological mechanism that prevents the development of hypoxemia secondary to a regional decrease in the ventilation–perfusion ratio (the intrapulmonary shunt effect). Calcium plays a critical role in
Gizzatullin Timour, Vallot Fréderic, Simonet Olivier, Didier Ndjekembo Shango   +3 more
doaj   +1 more source

Effects of process variables on micromeritic properties and drug release of non-degradable microparticles [PDF]

, 2011
Introduction: The purpose of this investigation was to evaluate microencapsulated controlled release preparation of theophylline using Eudragit RS 100 as the retardant material with high entrapment efficiency.
Barar, Jaleh, Jelvehgari, Mitra, Nokhodchi, Ali, Shadrou, Sanam, Valizadeh, Hadi   +4 more
core   +3 more sources

Functional and Transcriptional Disruption of Hepatic ABC Transporters by Environmentally Relevant Short‐Chain Per‐ and Polyfluoroalkyl Substances (PFAS)

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 12, December 2025.
Low‐dose short‐chain PFAS exposures enhance hepatic ABC transporter activity and expression, revealing that environmentally relevant concentrations can reprogram xenobiotic transport pathways and potentially influence drug metabolism, bile acid handling, and lipid homeostasis, highlighting a molecular link between chronic PFAS exposure and altered ...
Gracen E. Collier, Ramon Lavado
wiley   +1 more source

Calcium channel blockers for acute traumatic brain injury. [PDF]

, 2003
BACKGROUND: Acute traumatic brain injury is a major cause of death and disability. Calcium channel blockers (calcium antagonists) have been used in an attempt to prevent cerebral vasospasm after injury, maintain blood flow to the brain, and so prevent ...
Goldfrad, C, Langham, J, Rowan, K, Shaw, D, Teasdale, G   +4 more
core   +1 more source