Results 61 to 70 of about 15,118 (218)
Intracerebral Hemorrhage: Advances, Knowledge Gaps, and Future Directions
This review provides a comprehensive synthesis of current research on the epidemiology, pathophysiological mechanisms, imaging characteristics, treatment delays, clinical management strategies, neural repair, and prognostic prediction of intracerebral hemorrhage (ICH).
Tao Liu +6 more
wiley +1 more source
A simple, sensitive and reproducible reversed-phase liquid chromatographic method has been developed and validated for the determination of nicardipine hydrochloride (NC) in pure, pharmaceutical preparations, human plasma and the study of the ...
Sheikha Mohammed Al-Ghannam +1 more
doaj +3 more sources
Comparison of Oral Nicardipine and Intravenous Magnesium Sulfate for Preterm Labor Pain Management [PDF]
Background and objectives 2% of all pregnancies terminate before 32 weeks and 12.5% of them before 37 weeks of gestation. Medical treatment by contraction inhibitors is the most common strategy for management of preterm labor pain.
M. Ghasemi, F. Aghaie Zadah, M. Movahedi
doaj +2 more sources
The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008.
Ravi Iyengar
core +2 more sources
ABSTRACT Hypertensive disorders in pregnancy (HDP) are a major cause of maternal and perinatal morbidity and mortality. The impact of HDP on labor stage duration and maternal and neonatal outcomes in nulliparous women remains unclear. To assess labor stage duration and maternal and neonatal outcomes in nulliparous women with HDP. A retrospective cohort
Hao Zhu +4 more
wiley +1 more source
Acute Vasoreactivity Testing With Nicardipine in Patients With Pulmonary Arterial Hypertension
Acute vasoreactivity testing for patients with pulmonary arterial hypertension (PAH) has been reported to be useful to identify patients with sustained beneficial response to oral calcium-channel blockers (CCBs), but there is a risk of exacerbation ...
Yukihiro Saito +15 more
doaj +1 more source
Randomized, open-label, phase 1/2a study to determine the maximum tolerated dose of intraventricular sustained release nimodipine for subarachnoid hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]) [PDF]
BACKGROUND AND PURPOSE—: We conducted a randomized, open-label, phase 1/2a, dose-escalation study of intraventricular sustained-release nimodipine (EG-1962) to determine safety, tolerability, pharmacokinetics, and clinical effects in aneurysmal ...
Aldrich, Francois +10 more
core +3 more sources
Trials are mostly reassuring regarding antihypertensive effects on fetal (FHR) or neonatal heart rate (neoHR), but observational studies raise concerns about beta‐blockers, particularly the alpha/beta‐blocker labetalol. Clinicians should ascribe adverse fetal or neonatal heart rate effects to evolving underlying placental dysfunction or newborn illness,
Akalya Ganeshamoorthy +9 more
wiley +1 more source
Prognostic significance of short-term blood pressure variability in acute stroke [PDF]
Background and Purpose— Blood pressure variability (BPV) may be an important prognostic factor acutely after stroke. This review investigated the existing evidence for the effect of BPV on outcome after stroke, also considering ...
Manning, Lisa S. +3 more
core +1 more source
Abstract Hypertensive crises require rapid blood pressure control to prevent stroke and myocardial injury. Despite Cleviprex's efficacy, its high cost limits accessibility in China. This Phase III, multicenter, randomized, double‐blind study evaluated the efficacy and safety of a generic clevidipine (China's first injectable generic clevidipine ...
Xiaoning Han +32 more
wiley +1 more source

