Transversus abdominis plane block reduces remifentanil and propofol consumption, evaluated by closed-loop titration guided by bispectral index. [PDF]
, 2018 The present prospective, randomized, double-blind study aimed to determine the impact of transversus abdominis plane (TAP) block on propofol and remifentanil consumption, when administered by closed-loop titration guided by processed ...
Jiang, Mei-Ru +7 more
core
抗原および抗ヒトIgEに対する抗塩基球の反応性. 3.Ca2(+)の細胞内流入およびヒスタミン遊離 [PDF]
, 1992 The release mechanism of chemical mediators from basophils and mast cells was discussed when these cells were stimulated by different antigens and anti-IgE. 1. Ca(2+) influx into mast cells increased after stimulation by antigen.
Kimura, Ikuro +5 more
core +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, Volume 599, Issue 18, Page 2557-2570, September 2025.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Breaking the Barrier: Unraveling the No‐Reflow Phenomenon in Cardiovascular Medicine
Catheterization and Cardiovascular Interventions, Volume 106, Issue 3, Page 1937-1945, September 1, 2025.ABSTRACT The no‐reflow phenomenon is a stubborn and often devastating complication in cardiovascular medicine, where blood flow is restored to an artery, yet the microvasculature remains unresponsive. First identified in 1967, this phenomenon has haunted clinicians and researchers alike, particularly in the context of acute myocardial infarction (AMI).
Stephanie Howes +9 more
wiley +1 more source
Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]
, 2007 This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall.
Bolton, TB +5 more
core +3 more sources
Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery
The FASEB Journal, Volume 39, Issue 16, 31 August 2025.Developing an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Dara Khosrowshahi +2 more
wiley +1 more source
Disclosure and adverse effects of complementary and alternative medicine used by hospitalized patients in the North East of England [PDF]
, 2012 Objectives: This study aimed to investigate the prevalence, disclosure and adverse effects of complementary and alternative medicine (CAM) use in hospitalised patients, and to explore the associations between patients’ perceived side-effects and relevant
Baqir, wasim +3 more
core +2 more sources
Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine
European Journal of Organic Chemistry, Volume 28, Issue 23, June 23, 2025.Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng +2 more
wiley +1 more source
Human enteric neurons: morphological, electrophysiological, and neurochemical identification [PDF]
, 2014 BACKGROUND: Access to tissue, difficulties with dissection, and poor visibility of enteric ganglia have hampered electrophysiological recordings of human enteric neurons.
Brookes, SJH +3 more
core +2 more sources