Results 141 to 150 of about 424,898 (313)

Breast cancer recurrence prediction with deep neural network and feature optimization

open access: yesAutomatika
Breast cancer remains a pervasive global health concern, necessitating continuous efforts to attain effectiveness of recurrence prediction schemes. This work focuses on breast cancer recurrence prediction using two advanced architectures such as Long ...
Arathi Chandran R I, V Mary Amala Bai
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Utilisation of Nile crocodile (Crocodylus niloticus) offal meal waste by-products as a novel protein substrate in the formulation of diets for Jumbo quail

open access: yesDiscover Agriculture
This study evaluated the effects of incorporating full-fat crocodile offal meal (COM) in Jumbo quail diets as a replacement for soybean meal. A total of 256, one-week-old quail were assigned to 32 cages (8 birds/cage) in a completely randomized design ...
AKho Gila   +2 more
doaj   +1 more source

Short communication: Effects of polyethylene glycol treatment on the chemical composition and in vitro dry matter degradability of Searsia lancea leaves

open access: yesSouth African Journal of Animal Science
This study investigated the effects of incremental levels of polyethylene glycol (PEG) treatment on the chemical composition and in vitro dry matter degradability (IVDMD) of Searsia lancea leaves. Polyethylene glycol was sprayed onto S. lancea leaves at
O. Hawu   +5 more
doaj   +1 more source

Classification and Comparison of Niche Services for Developing Strategy of Medical Tourism in Asian Countries

open access: yes, 2012
Medical tourism is a new trend in medical service. It is booming not only in Asian countries but also in European and South American countries. Worldwide competition of medical service is expected in the future, and niche service will be a " ...
陳宏基;郭信智;鍾國彪;張家寧;蘇喜;楊銘欽   +1 more
core  

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

A Novel Drug‐Loaded Porous Parylene Electrode for Targeted Anti‐Inflammatory Therapy and Hearing Preservation in Cochlear Implantation

open access: yesAdvanced Healthcare Materials, EarlyView.
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang   +11 more
wiley   +1 more source

Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction

open access: yesBMC Medicine
Background The role of one-carbon metabolism and related B-vitamins in cognitive function in ageing is well-documented, particularly for folate and vitamin B12, with vitamin B6 and riboflavin receiving much less attention.
Shane Gordon   +13 more
doaj   +1 more source

How Niche Is Niche? Measuring Individuals’ Perception of Technology Niche [PDF]

open access: yesProceedings of the Annual Hawaii International Conference on System Sciences, 2019
openaire   +2 more sources

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans   +7 more
wiley   +1 more source

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