Results 101 to 110 of about 11,857 (244)

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Unveiling the mysteries of Asian herbivores resource partitioning in tropical wet-grassland ecosystem

Global Ecology and Conservation
Ecological niche partitioning is fundamental for the coexistence of sympatric species. However, the relationship between herbivore body size and forage availability on resource segregation and selection remains debatable.
Anita Devi, Monika Sharma, Ruchi Badola, Syed Ainul Hussain   +3 more
doaj   +1 more source

Niche breadth explains the range size of European-centred butterflies, but dispersal ability does not. [PDF]

Glob Ecol Biogeogr, 2023
Hausharter J, Rashid S, Wessely J, Strutzenberger P, Moser D, Gattringer A, Fiedler K, Hülber K, Dullinger S.   +8 more
europepmc   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

Ecomorphology and use of food resources: inter- and intraspecific relationships of fish fauna associated with macrophyte stands

Neotropical Ichthyology
Based on the form-function interaction and its consequence to niche exploitation by fish species, the study aimed to identify ecomorphological patterns and to investigate the possibility of explaining the trophic niche breadth using the pattern of ...
Aline V. R. Prado, Erivelto Goulart, João P. A. Pagotto   +2 more
doaj   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Data for niche breadth predicts climate vulnerability

Biodiversity is essential for ecosystem stability, yet it is declining at an accelerating rate worldwide. Terrestrial vertebrates, as representative taxa, are facing severe threats, which willbe further exacerbated by future climate change. Understanding the climate change vulnerability of terrestrial vertebrates and identifying the key factors driving
Yuan, Ye, Yao, Liang
openaire   +1 more source

Self‐Cooling Molecular Spin Qudits

Advanced Materials, EarlyView.
A material made of [GdEr] molecular dimers can encode a qudit and perform as a magnetic refrigerant. Microwave resonant pulses coherently manipulate its 16 spin states, while direct demagnetization measurements cool the material and a device down to temperatures below 1 K.
Elías Palacios, David Aguilà, David Gracia, Diamatoula Maniaki, Leoní A. Barrios, Alessandro Chiesa, Jesús I. Martínez, Valentin Novikov, Olivier Roubeau, Stefano Carretta, Marco Evangelisti, Guillem Aromí, Fernando Luis   +12 more
wiley   +1 more source

Climate change-related growth improvements in a wide niche-breadth tree species across contrasting environments. [PDF]

Ann Bot, 2023
Fajardo A, Gazol A, Meynard PM, Mayr C, Martínez Pastur GJ, Peri PL, Camarero JJ.   +6 more
europepmc   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source