Results 81 to 90 of about 266,972 (277)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Appendix A. Niche breadth calculations and properties.

open access: yes, 2016
Niche breadth calculations and ...
Jurek Kolasa (287315)   +2 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

On the Time-like Curves of Constant Breadth in Minkowski 3-Space [PDF]

open access: yes, 2008
A regular curve with more than 2 breadths in Minkowski 3-space is called a Smarandache breadth curve. In this paper, one studies a special case of Smarandache breadth curves. Some characterizations of the time-like curves of constant breadth in Minkowski
Yilmaz, Suha, Turgut, Melih
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Niche Breadth: Causes and Consequences for Ecology, Evolution, and Conservation

open access: yes, 2020
Niche breadth is a unifying concept spanning diverse aspects of ecology, evolution, and conservation biology. Niche breadth usually refers to the diversity of resources used or environments tolerated by an individual, population, species, or clade.
Emery, Nancy C   +7 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Differential use of nest materials and niche space among avian species within a single ecological community

open access: yesEcology and Evolution
Differential use of resources among bird species has been examined extensively in diet and nesting sites, but few studies have assessed this regarding avian nest materials.
Michael E. Akresh   +4 more
doaj   +1 more source

Bird specimen number linked with species trait and climate niche breadth

open access: yesAvian Research
Biological specimens are fundamental for taxonomy and flora/fauna research. More importantly, they also play crucial roles in recording environmental impacts on morphology and behavior, which is vital for biodiversity research and conservation.
Xiaoyu Duan   +6 more
doaj   +1 more source

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