Results 101 to 110 of about 282,271 (308)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Dual role for Headcase in hemocyte progenitor fate determination in Drosophila melanogaster.

open access: yesPLoS Genetics
The hematopoietic organ of the Drosophila larva, the lymph gland, is a simplified representation of mammalian hematopoietic compartments, with the presence of hemocyte progenitors in the medullary zone (MZ), differentiated hemocytes in the cortical zone (
Bayan Kharrat   +8 more
doaj   +1 more source

Transcriptionally and Functionally Distinct Mesenchymal Subpopulations Are Generated from Human Pluripotent Stem Cells

open access: yesStem Cell Reports, 2018
Summary: Various mesenchymal cell types have been identified as critical components of the hematopoietic stem/progenitor cell (HSPC) niche. Although several groups have described the generation of mesenchyme from human pluripotent stem cells (hPSCs), the
Chee Jia Chin   +8 more
doaj   +1 more source

Defining the Gay Tourist Niche: Marketing and Ethical Considerations [PDF]

open access: yes
Niche tourism is associated with the differentiation, competitive advantage, and sustainability, of tourist destinations. However, limitations and moral implications of niche strategies have been raised.
Canavan, Brendan
core  

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

open access: yes, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H.   +3 more
core   +1 more source

The Role of Lymphatic Niches in T Cell Differentiation

open access: yesMolecules and Cells, 2016
Long-term immunity to many viral and bacterial pathogens requires CD8(+) memory T cell development, and the induction of long-lasting CD8(+) memory T cells from a naïve, undifferentiated state is a major goal of vaccine design. Formation of the memory CD8(+) T cell compartment is highly dependent on the early activation cues received by naïve CD8(+) T ...
Capece, Tara, Kim, Minsoo
openaire   +3 more sources

Building a Framework for Sexual and Reproductive Healthcare in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, Accepted Article.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Evaluation of the Potential of Laser Shock Peening Compared with Cold Expansion for Improving Fatigue Resistance of Riveted Lap Joints of Aerospace Grade 7175 Al Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar   +6 more
wiley   +1 more source

Provenance does matter: links between winter trophic segregation and the migratory origins of European robins [PDF]

open access: yes, 2016
Amongst migratory species, it is common to find individuals from different populations or geographical origins sharing staging or wintering areas.
Bearhop, Stuart,   +7 more
core   +1 more source

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