Results 51 to 60 of about 1,130,240 (351)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Phytoplankton communities in different season in the coastal area of Kawasi, the western part of Obi Island, North Maluku, Indonesia [PDF]

BIO Web of Conferences
Plankton communities are one of the groups monitored to assess environmental conditions. West Obi Island is known for its fisheries resources and is one of Indonesia’s largest Nickel mining areas in North Maluku, Indonesia.
Lestari Dea Fauzia, Salsabila Afviya, Octaviandini Niken, Cakasana Nadya, Pasaribu Riza Aitiando, Prayogo Windy, Sujatno Retno Dewi Handayani, Hutami Prasari Risky, Setyabud Pandu, Ahadyatulakbar Farel   +9 more
doaj   +1 more source

Composition, Phase Structure, and Corrosion of Nickel-Free and Nickel-Containing Stainless Steel Orthodontic Wires [PDF]

, 2014
Stainless steel wires have long been used in orthodontics. The austenitic stainless steel used in orthodontics contains approximately 18 wt% chromium and 8 wt% nickel. Nickel improves the corrosion resistance and helps maintain the austenite structure of
Rakalla, Amrita
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Institutional Anomie, Market-Based Values and Anti-Immigrant Attitudes: A Multilevel Analysis in 28 European Countries

International Journal of Conflict and Violence, 2022
Individuals who are strongly oriented towards market-based values are more likely to devalue groups identified as ”unprofitable” from an economic point of view. Drawing on insights from Institutional Anomie Theory (IAT), this study explores economically
Amelie Nickel
doaj   +1 more source

Some observations on the ecology and phytochemistry of nickel-accumulating alyssum species from the Iberian peninsula : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]

, 1980
Experiments were carried out on the tolerance to, and uptake of nickel by Iberian subspecies of A. serpyllifolium. Two of these subspecies, the serpentinic-endemics s.sp. lusitanicum (from Bragança, Portugal) and s.sp.
Shaw, Sugirthamani
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Application and Development of Smart Mine in China [PDF]

MATEC Web of Conferences, 2019
The development of coal mining from ancient times to today has experienced the artificial stage, the mechanized mining stage, and the automated mining stage. Now it is developing towards a safer, greener and more efficient unmanned and smart mine.
Xu Ying, Wei Junqiang, Zhou Xiekang, Sun Feng   +3 more
doaj   +1 more source

Assessment of skin in patients with systemic sclerosis using high‐frequency ultrasound and shear wave elastography: A comparative study with histology, molecular and clinical parameters

Arthritis Care &Research, Accepted Article.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histological markers of skin fibrosis has not been reported. We evaluated the US‐based skin assessments for their face validity (differentiation between involved SSc and ...
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuela Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source