Results 41 to 50 of about 6,284,359 (297)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

EFFECT OF NICKEL ADMINISTRATION ON SOME BIOCHEMICAL PARAMETERS AND OVARIAN HORMONES IN FEMALE RABBITS

open access: yesZagazig Journal of Pharmaceutical Sciences, 1996
This study was designed to clarify the toxic effect of low and high doses of nickel on reproductive functions of immature rabbits treated with PMSG ,with trials to restrict the harmful effects of nickel administration Thirty seven immature female New ...
Abdel-Mohsen Hamam   +2 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

ADSORPTIVE REMOVAL OF NICKEL (II) USING LUFFA CYLINDRICA: EFFECT OF NaCl CONCENTRATION ON EQUILIBRIUM AND KINETIC PARAMETERS

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2018
In this study, biosorption of Nickel (II) from saline solutions by Luffa Cylindrica, was studied as a function of pH, initial Nickel (II) and NaCl concentrations in a batch system.
CHIFAA AD   +4 more
doaj  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Contact sensitization to metals in dental exposures in Bulgaria

open access: yesBiotechnology & Biotechnological Equipment, 2018
The purpose of this study was to evaluate the incidence of contact sensitization to metals used in dental practice among students of dental medicine, students from a dental technician school, dental professionals and patients. A total of 128 participants:
Maya Lyapina   +8 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Assessment of nickel and chromium level in gingival crevicular fluid in patients undergoing orthodontic treatment with or without fluoridated tooth paste

open access: yesJournal of Pharmacy and Bioallied Sciences, 2021
Background: Release of metallic ions, especially nickel and chromium, present in orthodontic fixed appliance attachments such as brackets and archwires has been a basis of concern in current years.
Amrita Pritam   +5 more
doaj   +1 more source

Molecular mechanisms of nickel carcinogenesis: nickel binding to histone H4 and Cap43 protein [PDF]

open access: yes, 2005
The carcinogenicity of nickel compounds has been confirmed and corroborated by numerous epidemiological studies in humans and carcinogenesis bioassays in animals.
Medici, Serenella   +2 more
core  

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