Results 111 to 120 of about 106,852 (270)
ABSTRACT Myocardial infarction (MI) is the most severe clinical manifestation of coronary artery diseases (CVD) and serves as a critical driver of sudden cardiac death and heart failure (HF). Its pathophysiology begins with the abrupt cessation of coronary blood flow, leading to severe ischemia and subsequent cardiomyocyte necrosis. This study aimed to
Cheng‐Cheng Wei +2 more
wiley +1 more source
The IceShark, an effective method for sampling plankton under sea ice
Abstract Seasonal sea ice plays a crucial role in shaping coastal ecosystem dynamics throughout the circumpolar region. Of particular interest to oceanographers is the ice‐ocean interface which functions as a multidimensional habitat, supporting both sympagic algae and pelagic phytoplankton in the under‐ice surface waters.
Eleanor A. Barry +4 more
wiley +1 more source
2000 Men\u27s Cross Country Media Guide, George Fox ...
George Fox University Archives
core +13 more sources
No App, No Entry: Conceptualizing Digital Technology Captivity in Service Access
ABSTRACT We introduce Digital Technology Captivity (DTC), a form of consumer vulnerability that arises when digital technologies become the mandatory gateway to essential services. When access is tied to systems that feel unfamiliar, complex, or intimidating—and when preferred alternatives are limited—consumers may experience heightened vulnerability ...
Carolyn Wilson‐Nash +4 more
wiley +1 more source
Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou +6 more
wiley +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
ABSTRACT Purpose In diffusion MRI, vasogenic edema manifests as a major fraction of isotropic water that dilutes the anisotropic intra‐axonal portion of the signal. Many tractography algorithms mistake vasogenic edema for the white matter boundary and terminate tracking to prevent producing spurious streamlines.
Patryk Filipiak +6 more
wiley +1 more source
ABSTRACT Purpose Ultrahigh‐field MRI requires careful management of the specific absorption rate (SAR), which is subject and subject‐position dependent. Within‐scan subject motion may exacerbate local SAR exposure, necessitating large safety margins to prevent SAR underestimation, which hampers imaging performance.
Katherine Anna Blanter +4 more
wiley +1 more source
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel +5 more
wiley +1 more source

