Results 61 to 70 of about 10,296 (281)
American place names as the reflection of American mentality
Когниция, коммуникация, дискурс, 2018 The paper is aimed at revealing the American mentality through toponyms. The object of the research are the names of towns and states of the USA with the exception of those of Indian origin.
L. G. Brutian
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Advanced Science, EarlyView.USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen +7 more
wiley +1 more source
Yemînî’nin Fazîlet-nâme Adlı Eserinde Hz. Ali’nin Lakapları
SkadHz. Ali, İslam kültüründeki önemi, cesareti, kahramanlıkları ve manevî üstünlükleriyle pek çok edebî esere ilham kaynağı olmuştur. Özellikle Fazîlet-nâme adlı eser, 16. yüzyılda yazılmış ve Hz.
Orhan Tokat
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Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
The Origin Of Nyc’s Nickname The Big Apple [PDF]
, 1993 The expression The Big Apple, meaning something special, out of the ordinary, world class is traced from its adoption as the nickname of New York City in 1971 back through time, to the jazz culture of the 1930s and ultimately to its apparent origins ...
Cohen, Gerald Leonard
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A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Advanced Science, EarlyView.Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
Advanced Science, EarlyView.This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
The cognitive nature of Ukrainian nickname construction
Cognitive Studies | Études cognitives, 2018 The cognitive nature of Ukrainian nickname construction This article is devoted to the study of the cognitive nature of the informal anthroponym creation mechanisms in the everyday communication of Ukrainian speakers. The article traces the role of the
Nataliia Shulska +2 more
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Advanced Science, EarlyView.TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu +9 more
wiley +1 more source
Springfield College Nickname/Mascot Preference Poll (1994)
, 1994 This is the Springfield College Nickname/Mascot 1994 Preference Poll that was sent out to the community in the Fall of 1994. The poll was in regards to changing the current nickname/mascot from "Chiefs" to one of Four choices, including Athletics ...
Springfield College;
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