Results 31 to 40 of about 36,998 (271)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Functional and Language Features of Nicknames of German-Speaking Users of Humorous Internet Sites

open access: yesРазвитие образования, 2020
The author of the article outlines that nicknames represent a relatively new linguistic phenomenon in virtual communication, which has been the subject of many contemporary studies.
Elena V. Zakharova
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Function, familiarity or fun?: Nicknames in Rehoboth, Namibia [PDF]

open access: yes, 1988
African Studies Seminar series. Paper presented 24 October 1988Naming practices and the use of nicknames have received a fair amount of attention from anthropologists over the years - particularly from those who have worked in the Mediterranean region
Pearson, Patrick
core  

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Old Norse Nicknames: Origins and Terminology

open access: yesNames, 2019
Nicknames, which occur in all cultures and time periods, play a unique role in highlighting identity. The pool of first names has always been relatively limited, thus most people were identified by their nicknames, especially before surnames became ...
Paul R. Peterson
doaj   +1 more source

Nicknames in Video Gaming: Functional Use and Variation [PDF]

open access: yesВопросы ономастики, 2020
The article discusses the use of nicknames in online games (specifically, the Dota 2 game) which constitutes a completely new field of onomastic research.
Margarita A. Klimova
doaj   +1 more source

Морфологічні способи творення неофіційних антропонімів в англійській, німецькій та українській мовах [PDF]

open access: yes, 2012
This article dwells upon the problem of nicknames’ origin in English, German, and Ukrainian. The author analyzes three thematic nickname groups: political, criminal, and school and university nicknames in the languages. This research concerns nicknames’
Катернюк, Вікторія Вікторівна
core  

Winter is here: summarizing Twitter streams related to pre-scheduled events [PDF]

open access: yes, 2019
Pre-scheduled events, such as TV shows and sports games, usually garner considerable attention from the public. Twitter captures large volumes of discussions and messages related to these events, in real-time.
Andy, Anietie   +2 more
core   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

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