Results 161 to 170 of about 458,722 (380)
Frontiers in PharmacologyTobacco-free nicotine pouches are new nicotine products for oral consumption. They can contain very high nicotine amounts that have not been addressed with clinical studies yet.
Nadja Mallock-Ohnesorg +14 more
doaj +1 more source
STUDIES ON INTRAVENOUS WATER DIURESIS AND NICOTINE AND PITRESSIN ANTIDURESIS IN NORMAL SUBJECTS AND PATIENTS WITH LIVER DISEASE 1 [PDF]
, 1953 Stanley H. Bernstein +5 more
openalex +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams +7 more
wiley +1 more source
Effectively Regulating E-Cigarettes and Their Advertising—and the First Amendment [PDF]
, 2015 If tobacco smoking did not exist in the United States, there would be no reason, from a public health perspective, to allow addictive, nicotine-containing e-cigarettes to be marketed and sold. Because e-cigarette use, by itself, is neither beneficial nor
Lindblom, Eric N
core +1 more source
Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology
Eye &ENT Research, EarlyView.Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang +9 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
Specificity of Nicotinic Acid as a Growth Factor For Isolated Pea Roots1 [PDF]
, 1940 James Bonner
openalex +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Environmental Toxicology and Chemistry, EarlyView.Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz +4 more
wiley +1 more source