Results 191 to 200 of about 467,845 (329)

Human brain organoid-on-a-chip to model prenatal nicotine exposure.

Lab on a Chip, 2018
Yaqing Wang, Li Wang, Yujuan Zhu, J. Qin
semanticscholar   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Reconsidering Ondansetron for Smoking Cessation: A Call for Renewed Investigation. [PDF]

Pharmacol Res Perspect
Tam A, Munsar Z, Opler DJ.
europepmc   +1 more source

Influence of the Skin Temperature on the Axon Reflex Pilomotion Produced by Nicotine in Human Skin

, 1979
Minoru Sakurai
openalex   +2 more sources

Cloud‐Based GWAS Platform: An Innovative Solution for Efficient Acquisition and Analysis of Genomic Data

Med Research, EarlyView.
This graphical abstract illustrates the cloud‐based GWAS platform as a hub that integrates six major multiomics domains: phenomics, neuroscience, proteomics, microbiomics, metabolomics, and nutrigenomics. The platform unifies diverse data types—including clinical phenotypes, neuroimaging, plasma proteomics, microbiome profiles, metabolic biomarkers ...
Xiaohong Ke, Kailai Li, Aimin Jiang, Yasi Zhang, Qi Wang, Zhengrui Li, Jian Zhang, András Hajd, Wenjie Shi, Ulf Kahlert, Anqi Lin, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Does e-cigarette nicotine strength influence substitution for combustible cigarettes? [PDF]

J Exp Anal Behav
Stein JS, Tegge AN, Brown JM, Curran KM, Bickel WK.   +4 more
europepmc   +1 more source

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

Nature, 2008
T. Thorgeirsson, F. Geller, P. Sulem, T. Rafnar, Anna K. Wiste, K. Magnússon, A. Manolescu, G. Thorleifsson, H. Stefánsson, A. Ingason, S. Stacey, J. Bergthórsson, S. Thorlacius, J. Gudmundsson, Thorlákur Jónsson, Margret Jakobsdottir, J. Saemundsdottir, O. Olafsdottir, L. Gudmundsson, G. Bjornsdottir, K. Kristjánsson, H. Skuladottir, H. Isaksson, T. Gudbjartsson, Gregory T. Jones, T. Mueller, A. Gottsäter, A. Flex, K. Aben, F. Vegt, P. Mulders, D. Isla, M. Vidal, L. Asín, B. Saez, L. Murillo, T. Blondal, H. Kolbeinsson, J. Stefánsson, I. Hansdottir, V. Runarsdottir, R. Pola, B. Lindblad, A. V. Rij, B. Dieplinger, M. Haltmayer, J. Mayordomo, L. Kiemeney, Stefán E. Matthíasson, H. Oskarsson, Thorarinn Tyrfingsson, D. Gudbjartsson, J. Gulcher, S. Jonsson, U. Thorsteinsdóttir, A. Kong, K. Stefánsson   +56 more
semanticscholar   +1 more source

Levodopa Disrupts Activity Patterns and Encoding of Movement in Striatal Cholinergic Interneurons of Behaving Mice

Movement Disorders, EarlyView.
Abstract Objectives Levodopa treatment, the gold standard therapy for Parkinson's disease, can lead to levodopa‐induced dyskinesias (LIDs). Recent studies in acute brain slices have implicated the neural dynamics of striatal cholinergic interneurons (CINs) in the pathophysiology of LID, reporting that their discharge becomes more bursty in dyskinetic ...
Yara Atamna, Lior Tiroshi, Nadine Wattad, Naomi Gilin, Shelly Gilad, Noa Berkowitz, Joshua A. Goldberg   +6 more
wiley   +1 more source

Racial and ethnic variation in perceived relative harm of tobacco and nicotine products: an experimental study. [PDF]

BMJ Public Health
DeAtley T, Stone MD, Johnson AC, Mercincavage M, Villanti AC, Wetter DW, Audrain-McGovern J, Delnevo C, Strasser AA.   +8 more
europepmc   +1 more source

Functional Magnetic Resonance Imaging (fMRI) Signatures of Progression and Phenoconversion in Prodromal Synucleinopathies

Movement Disorders, EarlyView.
Abstract Background Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal manifestation of synucleinopathies and provides a critical window to identify early markers of progression to Parkinson's disease (PD) and dementia with Lewy bodies (DLB).
Lachlan Churchill, Anna Ignatavicius, Ajay Konuri, Jack Anderson, Natasha Taylor, Simon J.G. Lewis, Elie Matar   +6 more
wiley   +1 more source