Results 191 to 200 of about 458,722 (380)

CYP2C19 Loss‐of‐Function Is an Independent Risk Factor of Coronary Artery Disease in Patients With Hypertension

Journal of Clinical Laboratory Analysis, EarlyView.
The relationship between Cytochrome P450 2C19 (CYP2C19) polymorphisms and coronary artery disease (CAD) in hypertensive patients was analyzed. CYP2C19 loss‐of‐function, BMI ≥ 24.0 kg/m2, and history of alcoholism were independent risk factors for CAD in hypertensive patients.
Guoliang Wei, Bin Li, Hao Wang, Wenhao Chen, Kehui Chen, Weihong Wang, Shen Wang, Hui Zeng, Yuanliang Liu, Yue Zeng, Hui Rao   +10 more
wiley   +1 more source

Comparative study of ethanol, caffeine and nicotine on behavior of albino rats [PDF]

, 1921
David I. Macht, W. Bloom
openalex   +1 more source

Physiologically Based Pharmacokinetic Modeling to Predict Nicotine Pharmacokinetics of Nicotine Pouches Under Naturalistic Use Conditions

The Journal of Clinical Pharmacology, EarlyView.
Abstract Adult users of traditional tobacco products like combustible cigarettes (CC) or moist smokeless tobacco (MST) products can reduce exposure to toxicants by switching to potentially less harmful alternatives such as tobacco‐free nicotine pouches (NP). Nicotine exposure assessment is an important consideration to determine the switching potential
Ali Salehi, Mohamadi A. Sarkar, Jennifer H. Smith, Ali A. Rostami   +3 more
wiley   +1 more source

THE STEREOSPECIFICITY OF NICOTINE [PDF]

British Journal of Pharmacology and Chemotherapy, 1965
J. T. Hamilton, R. B. Barlow
openaire   +3 more sources

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source

THE DETERMINATION OF “FREE NICOTINE” IN TOBACCO: THE APPARENT DISSOCIATION CONSTANTS OF NICOTINE

, 1929
Hubert Bradford Vickery, George W. Pucher   +1 more
openalex   +1 more source

Nicotinic Acid Tolerance Test [PDF]

, 1947
Anna Erdei
openalex   +1 more source

Nicotinic receptors and nicotine addiction

Comptes Rendus. Biologies, 2009
openaire   +2 more sources

A Randomized Crossover Clinical Study to Assess the Effect of Oral Nicotine Pouches Used for Different Durations on Plasma Nicotine Pharmacokinetics in Healthy Oral Pouch Consumers

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oral nicotine pouches (NPs), although addictive and not risk‐free, have potential application for a tobacco harm reduction approach. This study aims to further characterize their ability to deliver nicotine effectively. This randomized seven‐way crossover PK study in healthy oral pouch consumers evaluated 11 and 20 mg NPs used for 10, 20, and ...
David Azzopardi, Elaine Brown, Filimon Meichanetzidis, Stacy Fiebelkorn, Linsey E. Haswell, George Hardie, Michael McEwan   +6 more
wiley   +1 more source

Reaction of Ethylene Oxide with Nicotinamide and Nicotinic Acid

, 1959
H.G. Windmueller, C.J. Ackerman, Howard Bakerman, Olaf Mickelsen   +3 more
openalex   +1 more source