Results 231 to 240 of about 458,722 (380)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Why We Need Greater, Not Less, Access to Reduced-Risk Nicotine Products. [PDF]

Cureus
Fearon IM, Murphy MA.
europepmc   +1 more source

Effect of Nicotinic Acid on the Incorporation of Radiocarbon into Cholesterol [PDF]

, 1958
Joseph M. Merrill
openalex   +1 more source

Pituri and Nicotin

The Journal of Physiology, 1890
W. Lee Dickinson, John Newport Langley
openaire   +4 more sources

Functional Magnetic Resonance Imaging (fMRI) Signatures of Progression and Phenoconversion in Prodromal Synucleinopathies

Movement Disorders, EarlyView.
Abstract Background Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal manifestation of synucleinopathies and provides a critical window to identify early markers of progression to Parkinson's disease (PD) and dementia with Lewy bodies (DLB).
Lachlan Churchill, Anna Ignatavicius, Ajay Konuri, Jack Anderson, Natasha Taylor, Simon J.G. Lewis, Elie Matar   +6 more
wiley   +1 more source

Nicotine Withdrawal Drives Aversive Behaviors by Recruiting Inhibitory Interpeduncular Nucleus Inputs to the Laterodorsal Tegmentum in Mice. [PDF]

J Neurosci
Monical A, McGehee DS.
europepmc   +1 more source

Microbial Degradation of Nicotine and Nicotinic Acid

, 1954
Takeshi Tabuchi
openalex   +2 more sources

Metabolism of nicotinamide and nicotinic acid in Neurospora crassa [PDF]

, 1958
T. K. Sundaram, K. Rajagopalan, P.S. Sarma   +2 more
openalex   +1 more source

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

Medicinal Research Reviews, EarlyView.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg, Tracie Widjaja, Adriaan P. IJzerman, Daan van der Es   +3 more
wiley   +1 more source

Receiving coupons and discounts for nicotine pouches is associated with current use of nicotine pouches among United States adults: Results from the population assessment of tobacco and health (PATH) study wave 7 (2022-2023). [PDF]

Drug Alcohol Depend Rep
Lee J, Merenda F, Weinberger AH.
europepmc   +1 more source