Results 41 to 50 of about 102,363 (294)

Neural signatures of cognitive flexibility and reward sensitivity following nicotinic receptor stimulation in dependent smokers : a randomized trial [PDF]

, 2017
IMPORTANCE Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence and by pharmacotherapies such as nicotine replacement therapy and varenicline tartrate may aid ...
Aronson, Sarah E., Lesage, Elise, Ross, Thomas J., Salmeron, Betty Jo, Stein, Elliot A., Sutherland, Matthew T.   +5 more
core   +2 more sources

Multiethnic Prediction of Nicotine Biomarkers and Association With Nicotine Dependence [PDF]

Nicotine & Tobacco Research, 2020
Abstract Introduction The nicotine metabolite ratio and nicotine equivalents are measures of metabolism rate and intake. Genome-wide prediction of these nicotine biomarkers in multiethnic samples will enable tobacco-related biomarker, behavioral, and exposure research in studies without ...
Andrew W. Bergen, Christopher S. McMahan, Stephen McGee, Carolyn M. Ervin, Hilary A. Tindle, Loïc Le Marchand, Sharon E. Murphy, Daniel O. Stram, Yesha M. Patel, Sungshim L. Park, James W. Baurley   +10 more
openaire   +3 more sources

SMART goals setting and biometric changes in obese adults with multimorbidity: Secondary analysis of a randomized controlled trial

SAGE Open Medicine, 2019
Objectives: Clinicians recommend diet and exercise for overweight/obese patients. We conducted a secondary analysis of a randomized controlled clinical trial evaluating goal setting and pedometer use versus usual care on weight, waist circumference, and ...
Paul Y Takahashi, Stephanie M Quigg, Ivana T Croghan, Darrell R Schroeder, Jon O Ebbert   +4 more
doaj   +1 more source

Smoking characteristics and cessation in patients with thromboangiitis obliterans

Monaldi Archives for Chest Disease, 2016
Aim. Describe the smoking characteristics and the results of a smoking intervention programme involving 27 cigarette smokers with Thromboangiitis Obliterans (TAO). Methods.
C.A. Jiménez-Ruiz, L.C. Dale, J. Astray Mochales, L. Velázquez Buendía, I. de Granda Orive, A. Guirao García   +5 more
doaj   +1 more source

Relationship between Food Dependence and Nicotine Dependence in Smokers: A Cross-Sectional Study of Staff and Students at Medical Colleges

Medicina, 2019
Background and objectives: The aim of this study was to examine the relationship between nicotine dependence and food dependence in smokers. Smoking and obesity are both serious public health problems that give rise to diseases and increased medical ...
Yutaka Owari, Nobuyuki Miyatake, Hiromi Suzuki   +2 more
doaj   +1 more source

Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American [PDF]

, 2017
BACKGROUND: Smoking is a leading cause of preventable death. Early studies based on samples of twins have linked the lifetime smoking practices to genetic predisposition.
Beuten, Bierut, Biesalski, Bloom, Boyle, Carmelli, Dickson, Doll, Doll, Feng, Gabriel, Gerra, Hall, Heatherton, Hecht, Hines, Hinrichs, Hong, Huang, Israni, Kennedy, Kremer, Krueger, Laniado-Laborín, Lee, Lerman, Liu, Mackillop, Mangold, Olfson, Park, Price, Pritchard, Pruim, Purcell, Quail, Ripley, Sabol, Saccone, Shafey, Szklarczyk, Thorgeirsson, Thorgeirsson, Tucker, Tønnesen, Uhl, Vink, Wang, World Health Organization, Xie   +49 more
core   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

GABAB receptor allosteric modulators exhibit pathway-dependent and species-selective activity. [PDF]

, 2017
Positive modulation of the GABAB receptor (GABABR) represents a potentially useful therapeutic approach for the treatment of nicotine addiction. The positive allosteric modulators (PAMs) of GABABR GS39783 and BHF177 enhance GABA-stimulated [35S]GTP γS ...
Cameron, Michael, de Lourdes Ladino, Maria, Finn, MG, Griffin, Patrick R, Kaczanowska, Kasia, Li, Xia, Markou, Athina, McDonald, Patricia, Sturchler, Emmanuel   +8 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

Angewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat   +6 more
wiley   +2 more sources