Results 41 to 50 of about 1,153,102 (292)

Multiethnic Prediction of Nicotine Biomarkers and Association With Nicotine Dependence [PDF]

Nicotine & Tobacco Research, 2020
Abstract Introduction The nicotine metabolite ratio and nicotine equivalents are measures of metabolism rate and intake. Genome-wide prediction of these nicotine biomarkers in multiethnic samples will enable tobacco-related biomarker, behavioral, and exposure research in studies without ...
Andrew W. Bergen, Christopher S. McMahan, Stephen McGee, Carolyn M. Ervin, Hilary A. Tindle, Loïc Le Marchand, Sharon E. Murphy, Daniel O. Stram, Yesha M. Patel, Sungshim L. Park, James W. Baurley   +10 more
openaire   +3 more sources

Identifying the barriers of smoking cessation and predictors of nicotine dependence among adult Malaysian smokers: A cross-sectional study

, 2022
Introduction Proper understanding of the prevalence and determinants of nicotine dependence is crucial for developing and implementing effective tobacco control interventions.
Kirthanashree Arasu, Abiodun D. Obaromi, Yulan Lin, Thin M. Kyaw, Roy R. Marzo, Nermin A. Osman, Prem Kumar A/L Arivanandan, Kareem A. El-Fass, Keiswini Latchumana, Logithasan Murale Morgan   +9 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Affective temperaments in nicotine-dependent and non-nicotine-dependent individuals [PDF]

, 2016
Background One of the smoking risk factors influencing nicotine dependency may be human personality; however, few studies have examined the association between Akiskal’s affective temperaments and smoking in adults.
Ewa Stanisławiak, Włodzimierz Oniszczenko   +1 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Differences in Tobacco Use Among a Sample of At-Risk Chinese, Filipino, and Vietnamese Adult Men Living in the SF Bay Area

Tobacco Use Insights, 2019
Background: Smoking among Asian men has been studied, but differences in tobacco and cigarette use among US- and non-US-born Asian subgroups, especially those at risk for substance use or sexually transmitted diseases, has not been well-studied. Aims: To
Daniel E Toleran, Robynn S Battle, Phillip Gardiner   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Identifying determinants of varenicline adherence using the Theoretical Domains framework: a rapid review

BMC Public Health
Background Adhering to varenicline has been shown to significantly improve the chances of successfully quitting smoking, with studies indicating a twofold increase in 6-month quit rates.
Nadia Minian, Melissa Wong, Sowsan Hafuth, Terri Rodak, Alma Rahimi, Dea Gjomema, Jonathan Rose, Laurie Zawertailo, Matt Ratto, Peter Selby   +9 more
doaj   +1 more source

Nicotine dependence, its risk indicators, and exhaled carbon monoxide levels among the smokers in Bengaluru, India

Indian Journal of Community Medicine, 2018
Background: Tobacco is the significant cause of preventable death worldwide. The prevalence of smoking in India is 13.3%. Among the chemical constituents in the cigarette, nicotine is the one most often associated with dependence resulting in increased ...
P Sugavanesh, K Pushpanjali
doaj   +1 more source

Nicotine dependence as a risk factor for upper aerodigestive tract (UADT) cancers: A mediation analysis.

PLoS ONE, 2020
PurposeThis study investigated nicotine dependence as an independent risk factor for upper aerodigestive tract (UADT) cancers, including lung and head and neck cancers (HNC).
Sera Thomas, June C Carroll, M Catherine Brown, Zhou Chen, Maryam Mirshams, Devalben Patel, Kevin Boyd, Andrew Pierre, David P Goldstein, Meredith E Giuliani, Wei Xu, Lawson Eng, Elham Khodayari Moez, Geoffrey Liu, Rayjean J Hung   +14 more
doaj   +1 more source