Results 51 to 60 of about 1,153,102 (292)

Mapping the Social Network Structure and Composition of Black Individuals With Rheumatic and Musculoskeletal Conditions

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to describe the social networks of Black individuals with rheumatic and musculoskeletal conditions and understand the clustering of health‐related behaviors to inform future community‐based, peer‐led interventions. Methods We used an adapted Personal Network Survey for Clinical Research (PERSNET) to map the personal social ...
Taussia Boadi   +27 more
wiley   +1 more source

Technology-Enabled Collaborative Care for Type-2 Diabetes and Mental Health (TECC-D): Findings From a Mixed Methods Feasibility Trial of a Responsive Co-Designed Virtual Health Coaching Intervention

open access: yesInternational Journal of Integrated Care
Introduction: Type-2 diabetes (T2D) is a complex chronic condition associated with a lower quality of life due to disease specific distress. While there is growing support for personalized diabetes programs, care for mental health challenges is often ...
Diana Sherifali   +10 more
doaj   +1 more source

Analysis of nicotine dependence among daily smokers in China: evidence from a cross-sectional study in Zhejiang Province

open access: yesBMJ Open, 2022
Objective The current study aimed to assess the level of nicotine dependence and its influencing factors among daily smokers in Zhejiang, China.Setting The 2020 Global Adult Tobacco Survey was conducted in Zhejiang, China.Participants 1244 daily smokers ...
Yue Xu   +6 more
doaj   +1 more source

How Does Smoking and Nicotine Dependence Change After Onset of Vaping? A Retrospective Analysis of Dual Users

open access: yes, 2020
Introduction: Although some smokers switch to exclusive use of electronic cigarettes (e-cigarettes), others become dual users of combustible cigarettes and e-cigarettes.
Martínez, Úrsula   +20 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Investigating predictors of problematic alcohol, cannabis, and nicotine use among legal users of all three substances

open access: yesFrontiers in Psychiatry, 2023
BackgroundThe three most used substances—alcohol, cannabis, and nicotine—are frequently concurrently. Use of each substance has been connected to an increased probability of use of the other substances, and the problematic use of each substance has been ...
Aaron Shephard   +2 more
doaj   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia   +15 more
wiley   +1 more source

CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence

open access: yesScientifica, 2015
Each CYP2A6 gene variant metabolizes nicotine differently depending on its enzymatic activities. The normal nicotine metabolizer CYP2A6*1A is associated with high scores of nicotine dependence (5–10) on the Fagerström Test for Nicotine Dependence (FTND ...
Yawo Mawuli Akrodou
doaj   +1 more source

Assessment of nicotine dependence among smokers in Nepal: a community based cross-sectional study [PDF]

open access: yes, 2015
Background The Fagerström Test for Nicotine Dependence (FTND) and Heaviness of Smoking Index (HSI) are extensively used methods to measure the severity of nicotine dependence among smokers.
Anju Gautam   +3 more
core   +1 more source

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