Results 221 to 230 of about 199,124 (324)

Structural Connectivity Disruption and Structural–Functional Decoupling in Working Memory Networks Across Pre‐Dialysis and Maintenance Hemodialysis End‐Stage Renal Disease Patients

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This study examined structural connectivity (SC) and structural–functional coupling (SFC) within working memory (WM) networks in end‐stage renal disease. Pre‐dialysis patients showed disrupted frontoparietal connectivity and reduced coupling, associated with higher urea, lower sodium, and impaired WM performance.
Xiaoling Xu   +11 more
wiley   +1 more source

E-cigarettes versus combination nicotine replacement therapy following a recent failed quit attempt: a pragmatic randomized trial through state tobacco quitlines. [PDF]

open access: yesLancet Reg Health Am
Wagener TL   +8 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams   +7 more
wiley   +1 more source

Assessment of knowledge, attitude and practices of tobacco cessation counselling and nicotine replacement therapy among dental professionals. [PDF]

open access: yesJ Family Med Prim Care, 2023
Shete AV   +5 more
europepmc   +1 more source

Expectancies for Cigarettes, E-Cigarettes, and Nicotine Replacement Therapies Among E-Cigarette Users (aka Vapers)

open access: green, 2014
Paul T. Harrell   +7 more
openalex   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan   +6 more
wiley   +1 more source

Nicotine replacement therapy: insights into the mechanisms and potential of nicotine receptor pathway. [PDF]

open access: yesAm J Transl Res
Patidar N   +7 more
europepmc   +1 more source

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