Results 181 to 190 of about 78,616 (322)

Return to Spontaneous Circulation in a Patient With Cholinergic Syndrome at the Emergency Department of Buea Regional Hospital, Cameroon

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT With the increasing misuse of herbal treatment and pesticides, cases of cholinergic syndrome following herbal treatment or organophosphate poisoning have become increasingly common in our milieu. However, when advanced, mortality is high. We report the successful management of a case involving a 54‐year‐old African female with a known history ...
Bertolt Brecht Kouam Nteungue   +3 more
wiley   +1 more source

Organophosphate Poisoning: Insights From a Case Report of Acute Cholinergic Syndrome

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Organophosphate (OP) pesticides are widely used in agriculture and can cause acute cholinergic toxicity by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine. A 45‐year‐old male plumber was admitted to the emergency department 4 h after ingesting an unknown quantity of a 50% emulsifiable concentration of ...
Gudisa Bereda
wiley   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

open access: yesJournal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor   +3 more
wiley   +1 more source

Bisphenol A Treatment Impairs Synaptic Function in Human Cholinergic Neurons

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 10, October 2025.
Short‐term sublethal BPA exposure disrupts dendritic morphology, cholinergic synapse physiology, and activity‐dependent gene expression in human neurons. These alterations suggest impaired synaptic communication and plasticity, highlighting BPA's potential to affect the adult human brain even without inducing neuronal death.
Anna Maria Carrese   +7 more
wiley   +1 more source

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