Results 181 to 190 of about 76,692 (268)

Inside‐Out IP3‐Mediated G Protein‐Coupled Receptor Activation Drives Intercellular Ca2+ Signaling in the Vascular Endothelium

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
During endothelial cell Ca2+ wave propagation, IP3 in the initiating cell activates IP3Rs on the endoplasmic reticulum, releasing Ca2+ into the cytoplasm. We show that IP3 is required for signal propagation to neighboring cells and propose that this is due to activation of membrane‐bound pore‐dead IP3Rs, as part of a noncanonical signaling inside‐out ...
C. Buckley   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy