Results 181 to 190 of about 77,143 (337)
Light‐Activated Pharmacological Tools for Exploring the Cholinergic System
Medicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni +5 more
wiley +1 more source
NICOTINIC ACETYLCHOLINE RECEPTORS SUBSERVING NOCICEPTION IN THE DOG HINDLIMB
, 1970 Norio Taira +2 more
openalex +2 more sources
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.ABSTRACT The α7 nicotinic acetylcholine receptor (α7 nAChR) has emerged as a key target for treating cognitive dysfunction in neurological disorders such as Alzheimer's disease (AD) and schizophrenia. α7 nAChRs play essential roles in neurotransmission, neuroinflammation and synaptic plasticity, not only in neurons but also in glial cells, where they ...
Janus H. Magnussen
wiley +1 more source
Journal of Pharmacological Sciences, 2008 Acetylcholine (ACh) is a phylogenetically ancient molecule involved in cell-to-cell signaling in almost all life-forms on earth. Cholinergic components, including ACh, choline acetyltransferase, acetylcholinesterase, and muscarinic and nicotinic ACh ...
Significance Koichiro Kawashima +1 more
doaj
Properties of monoclonal antibodies to nicotinic acetylcholine receptor from chick muscle [PDF]
, 1984 Fuad Mehraban +2 more
openalex +1 more source
Advanced Functional Materials, Volume 35, Issue 23, June 5, 2025.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source
Chronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 105-116, June 2025.Donanemab, approved by the U.S. FDA in July 2024, targets amyloid plaques in the brain to treat Alzheimer's disease in patients with mild cognitive impairment or mild dementia. ABSTRACT Substantial research has been conducted to identify an efficient treatment for Alzheimer's disease (AD).
Nandhini Jayaprakash +1 more
wiley +1 more source
A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications. [PDF]
, 1984 André Klarsfeld +3 more
openalex +1 more source
Crop, Forage &Turfgrass Management, Volume 11, Issue 1, June 2025.Abstract Tobacco thrips (Frankliniella fusca Hinds) feeding can reduce peanut (Arachis hypogaea L.) yield and vector Tomato spotted wilt orthotospovirus (family Tospoviridae, genus Orthotospovirus). Visible injury caused by tobacco thrips feeding was recorded from 2013 to 2022 at one location in North Carolina when peanut was not treated with ...
Brittany Pendleton +9 more
wiley +1 more source