Results 181 to 190 of about 1,317,031 (279)

Pan-cancer expression, methylation, and prognostic significance of α7 nicotinic acetylcholine receptor in tumor immunology. [PDF]

Biochem Biophys Rep
Bai X, Ma T, Shi L, Wang P, Zhao D, Long J, Hai Y, You Y, Zhao R, Ma L.   +9 more
europepmc   +1 more source

Biodiversity effects on ecosystem functioning are driven by resource quality and contamination

Functional Ecology, Volume 40, Issue 10, Page 3133-3145, October 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Biodiversity–ecosystem functioning relationships are increasingly explained by species' traits and resource quality differences rather than richness alone, yet cross‐trophic effects and environmental context remain poorly resolved.
Alexander Feckler, Eva Lima‐Fernandes, Mirco Bundschuh, Frédérik De Laender, Christian Ritz, Verena C. Schreiner, Ralf Schulz, Matthias Wieczorek, Ralf B. Schäfer   +8 more
wiley   +1 more source

Organocatalytic Enantioselective Addition of Malonates to Cyclic Imines: A Short Total Synthesis of Tetraponerine T‐1

Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.
A stereoselective functionalization method of cyclic imines under mild organocatalytic conditions was developed. Bifunctional cinchona alkaloid catalysts combined with carefully optimized reaction conditions to suppress background reactivity enabled highly enantio‐ and diastereoselective addition reactions of malonates to cyclic imines.
Frederic Kölblin, Helma Wennemers
wiley   +2 more sources

Nicotinic Acetylcholine Receptor Modulation Distinguishes Clinical Benefits of Galantamine in Alzheimer's Disease. [PDF]

Sage Open Aging
Svintozelskiy PV, Wahlert AJ, Harrod C, Kay DG, Grady KP, Grossberg GT.   +5 more
europepmc   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Novel Nicotinic Acetylcholine Receptor Inhibitors Derived from Oleoylcholine Analogs. [PDF]

Acta Naturae
Vladykina MV, Kokaeva IS, Kasheverov IE, Gretskaya NM, Zinchenko GN, Tsetlin VI, Utkin YN, Bezuglov VV, Shelukhina IV.   +8 more
europepmc   +1 more source

Types of Neurons in the Myenteric Plexus of Human Gastric Corpus Identified by Multi‐Layer Immunohistochemical Coding and Vagal Tracing

Neurogastroenterology &Motility, Volume 38, Issue 10, October 2026.
Myenteric nerve cell bodies in the human gastric corpus were divided into 12 classes by the combinatorial expression of 15 neuronal markers, using multiplexed immunohistochemistry (1084 neurons from 7 individuals). Baskets of axonal varicosities from vagal or enteric sources were analyzed to detect targeted patterns of connectivity ...
M. E. Johnson, M. Wee, B. N. Chen, A. Humenick, R. A. Peterson, W. P. Yew, T. J. Hibberd, D. A. Wattchow, L. Kow, T. L. Powley, S. J. H. Brookes   +10 more
wiley   +1 more source

A critical role for α7 nicotinic acetylcholine receptor signaling in myeloid lineage cells in chronic neuropathic and inflammatory pain responses. [PDF]

J Pain
Swift A, Caillaud M, Graur A, McKiver BD, Toma W, Koseli E, Mann J, Lynch WB, Beierle JA, Thareja P, Yao EJ, Windle JJ, Beauzile H, Oh U, Thakur GA, Burton MD, Bryant CD, Kabbani N, Imad Damaj M.   +18 more
europepmc   +1 more source

Multi‐omics analysis of ion channels expressed by chicken embryo vestibular type I and type II hair cells

Experimental Physiology, Volume 111, Issue 10, Page 4894-4914, 1 October 2026.
Abstract Balance and gaze rely on the rapid and accurate detection and signalling of head movements by vestibular type I and type II hair cells. Signal transduction and transmission involve several types of ion channels, which are acquired progressively during hair cell differentiation and whose identity is known only in part.
Giulia Cheli, Roberta Giunta, Francesca Stella, Eleonora Guidi, Umberto Laforenza, Mariarosa Polimeni, Giancarlo Russo, Francesca Borgo, Lazarevic Dejan, Sergio Masetto   +9 more
wiley   +1 more source

Discovery and mechanism of negative allosteric modulation of the α7 nicotinic acetylcholine receptor by nanobodies. [PDF]

Proc Natl Acad Sci U S A
Barilone N, Vangelatou M, Marouf FZ, Dejean de la Bâtie G, Li Q, Lafaye P, Aymé G, Corringer PJ, Prevost MS.   +8 more
europepmc   +1 more source