Results 221 to 230 of about 1,317,031 (279)

The Pathway to Proof-of-Concept for BNC210, a Negative Allosteric Modulator of the Alpha-7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease. [PDF]

Clin Pharmacol Drug Dev
Rolan P, Doolin E, Paul D, Crossman J, Odontiadis M, Danjou P, Smith M, Papapetropoulos S.   +7 more
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Activation of the alpha 7 nicotinic acetylcholine receptor (CHRNA7) limits hypoxia-induced inflammatory responses and regulates collagens in cultured human granulosa cells†. [PDF]

Biol Reprod
Seßenhausen P, Caban KM, Schneider M, Eubler K, Kreitmair N, Schneider J, Dissen GA, Berg D, Berg U, Stöckl JB, Kunz L, Fröhlich T, Mayerhofer A.   +12 more
europepmc   +1 more source

α7 nicotinic acetylcholine receptor agonist attenuates lipopolysaccharide-induced acute kidney injury in mice by reducing CCL2 expression in macrophages. [PDF]

Sci Rep
Matsuo S, Uni R, Wu CH, Nakamura Y, Umene R, Surattichaiyakul B, Nangaku M, Inagi R, Nishino T, Inoue T.   +9 more
europepmc   +1 more source

Effects of Selective α7 Nicotinic Acetylcholine Receptor Stimulation in Oligodendrocytes: Putative Implication in Neuroinflammation. [PDF]

Cells
Guerriero C, Puliatti G, Di Marino T, Scanavino G, Matera C, Dallanoce C, Tata AM.   +6 more
europepmc   +1 more source

Computational model of alpha 7 nicotinic acetylcholine receptor in thalamic reticular nucleus neurons and their involvement in network states. [PDF]

PLoS One
Ullah A, Therrien K, Cressman JR, Kabbani N.   +3 more
europepmc   +1 more source

Optimizing PCR amplification of GC-rich nicotinic acetylcholine receptor subunits from invertebrates. [PDF]

Biochem Biophys Rep
Tanveer Khan M, Belgrano C, Rufener L, Horsberg TE, Bakke MJ.   +4 more
europepmc   +1 more source

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Nicotinic Acetylcholine Receptors and Imaging

Current Pharmaceutical Design, 2000
In vivo imaging techniques like positron emission tomography (PET) and single photon emission computed tomography (SPECT) offer the possibility to monitor human central nicotinic acetylcholine receptors (nAChRs) in a variety of central nervous system disorders. In the past, the only available PET radiotracer for imaging nAChRs in the human brain, [11C]-
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Nicotinic Acetylcholine Receptor Assays

Current Protocols in Pharmacology, 1999
AbstractNicotinic acetylcholine receptors (nAChRs) in peripheral tissues are localized almost exclusively to autonomic nerves and the motor end plates of striated musculature. Pharmacologic analyses of nicotinic receptor antagonist potencies can be conducted by assessing the ability of these compounds to inhibit responses elicited by preganglionic ...
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Nicotinic Acetylcholine Receptors and Epilepsy

Current Drug Target -CNS & Neurological Disorders, 2002
The neuronal nicotinic acetylcholine receptors (nAChRs) have multiple roles in the brain: they are involved in signal transduction by fast synaptic transmission, axo-axonic transmission, and in the modulation of presynaptic transmitter release. Presynaptic nAChRs can increase the release of excitatory as well as of inhibitory transmitters, and can ...
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