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The role of bile acid-activated receptor TGR5 in inflammation and liver diseases. [PDF]
Xiang H +5 more
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Rational Use of Bethanechol in Dogs and Cats with Bladder Dysfunction. [PDF]
Galluzzi F +4 more
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Neuromuscular System of Nematodes Is a Target of Synergistic Pharmacological Effects of Carvacrol and Geraniol. [PDF]
Stojković M +4 more
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Nicotinic Agonists and Psychosis
Current Drug Target -CNS & Neurological Disorders, 2002Schizophrenia patients have insufficient inhibitory processing of identical paired auditory stimuli. This deficient "auditory gating" is thought to have physiological relevance, and its severity correlates with certain measures of both positive and negative symptoms.
J K, Simosky, K E, Stevens, R, Freedman
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Effects of nicotinic agonists on the NMDA receptor
Brain Research, 1991The cholinergic nicotinic agonists (-)nicotine and lobeline were observed to partially inhibit whole-cell N-methyl-D-aspartate (NMDA)-induced responses in rat cortical neurons in culture. In addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, were able to displace [3H]dizocilpine
E, Aizenman, L H, Tang, I J, Reynolds
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Attentional effects of nicotinic agonists in rats
Neuropharmacology, 2003Nicotine can increase stimulus detection, response rate and speed in the five-choice serial reaction time task, a rodent test of attention. In the present experiments, four other nicotinic agonists with different pharmacological profiles were compared in the same procedure.
Britta, Hahn +4 more
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Binding of semirigid nicotinic agonists to nicotinic and muscarinic receptors.
Molecular Pharmacology, 1989Isoarecolone methiodide (1-methyl-4-acetyl-1,2,3,6-tetrahydropyridine methiodide) was previously shown to be among the most potent agonists tested at the frog neuromuscular junction. Because nicotinic receptors from different sources vary in their selectivities, isoarecolone methiodide as well as 19 additional congeners, most of which were also ...
C E, Spivak, J A, Waters, R S, Aronstam
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