Results 91 to 100 of about 90,845 (196)

Evolution of vertebrate nicotinic acetylcholine receptors

open access: yesBMC Evolutionary Biology, 2019
Background Many physiological processes are influenced by nicotinic acetylcholine receptors (nAChR), ranging from neuromuscular and parasympathetic signaling to modulation of the reward system and long-term memory.
Julia E. Pedersen   +2 more
doaj   +1 more source

Nitrosamines as nicotinic receptor ligands [PDF]

open access: yesLife Sciences, 2007
Nitrosamines are carcinogens formed in the mammalian organism from amine precursors contained in food, beverages, cosmetics and drugs. The potent carcinogen, NNK, and the weaker carcinogen, NNN, are nitrosamines formed from nicotine. Metabolites of the nitrosamines react with DNA to form adducts responsible for genotoxic effects. We have identified NNK
openaire   +2 more sources

Impulsive Behavior and Nicotinic Acetylcholine Receptors

open access: yesJournal of Pharmacological Sciences, 2012
Higher impulsivity is thought to be a risk factor for drug addiction, criminal involvement, and suicide. Excessive levels of impulsivity are often observed in several psychiatric disorders including attention-deficit/hyperactivity disorder and ...
Yu Ohmura   +2 more
doaj   +1 more source

Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors

open access: yeseLife, 2018
Dopamine (DA) neurons of the ventral tegmental area (VTA) integrate cholinergic inputs to regulate key functions such as motivation and goal-directed behaviors.
Romain Durand-de Cuttoli   +12 more
doaj   +1 more source

Insights into channel function via channel dysfunction [PDF]

open access: yes, 2003
The nicotinic synapse has been a touchstone for advances in neuroscience ever since Jean Nicot, the French ambassador to Portugal, sent some tobacco seeds home to Paris in 1550 with a note that the New World plant had interesting effects when smoked. Now
Leite, John F.   +2 more
core  

Prenatal Nicotine Exposure as a Teratogen in Neurological Pathways [PDF]

open access: yes, 2016
Attention-deficit/hyperactivity disorder (ADHD) is the most heritable and commonly diagnosed childhood psychiatric disorder with 4% of all children being diagnosed with this disorder.
Grover, Monica
core   +1 more source

The role of nicotinic receptors in alcohol consumption. [PDF]

open access: yesPharmacol Res, 2023
Kamens HM, Flarend G, Horton WJ.
europepmc   +1 more source

Cannabidiol as a modulator of α7 nicotinic receptors. [PDF]

open access: yesCell Mol Life Sci, 2022
Chrestia JF, Esandi MDC, Bouzat C.
europepmc   +1 more source

Variations in “Functional Site” Residues and Classification of Three-Finger Neurotoxins in Snake Venoms

open access: yesToxins
Three-finger toxins (3FTxs) are the largest group of nonenzymatic toxins found in snake venoms. Among them, neurotoxins that target nicotinic acetylcholine receptors are the most well-studied ligands.
R. Manjunatha Kini, Cho Yeow Koh
doaj   +1 more source

Nicotinic acetylcholine receptors

open access: yesScholarpedia, 2008
Pierre-Jean Corringer   +1 more
openaire   +1 more source

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