Results 41 to 50 of about 2,350,820 (217)
Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy
Equine Veterinary Journal, EarlyView.Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan +4 more
wiley +1 more source
Climate Justice in Sub‐Saharan Africa: Unequal Burdens and Pathways to Socially Just Adaptation
Sustainable Development, EarlyView.ABSTRACT Climate change in Sub‐Saharan Africa is often framed through vulnerability, resilience, and adaptation, yet these concepts alone do not fully explain the unequal social, economic, and political conditions shaping climate harm. This review examines climate change through a climate justice lens, focusing on unequal burdens, household welfare ...
Jacob Kwakye, Abraham Kwao
wiley +1 more source
Yeast, EarlyView.ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley +1 more source
Defective iron homeostasis and haematological abnormalities in Niemann-Pick disease type C1
, 2022 An investigation of iron-related parameters and haematological parameters in a mouse model of Niemann-Pick disease type C1 and in Niemann-Pick disease type C1 ...
Stephan Siebel +16 more
core +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source
Pfrieger's Digest Niemann-Pick Diseases Issue 7; May 2022-September 2022
, 2022 Summaries of latest research advances related to Niemann-Pick diseases, acid sphingomyelinase deficiency (ASMD) and Niemann-Pick type C disease (NPCD), based on selected peer-reviewed publications in scientific journals.
Fw, Pfrieger
core
Bidirectional links between Alzheimer's disease and Niemann–Pick type C disease
Neurobiology of Disease, 2014 Alzheimer's disease (AD) and Niemann–Pick type C (NPC) disease are progressive neurodegenerative diseases with very different epidemiology and etiology.
Martina Malnar +3 more
doaj +1 more source
Niemann-Pick type C fibroblasts are resistant against GalSph- and GlcSph-induced cell death.
, 2022 (A-C) Death of fibroblasts from healthy controls or patients with Niemann-Pick type C disease (NPC) treated with indicated concentrations of GalSph (A), GlcSph (B), or ebastine (C) for 48 hours was determined as in Fig 1A.
Kamilla Stahl-Meyer (14149669) +7 more
core +1 more source
Journal of Applied Entomology, EarlyView.ABSTRACT Liquid‐sprayable cellulose hydromulches (HM) are alternatives to plastic polyethylene (PE) mulches for weed suppression in organic agriculture. However, their impact on arthropod pests and natural enemies remains unexplored. Various HMs made of shredded newsprint, water and guar gum were compared against white‐on‐black PE mulch, paper sheet ...
Andres Torres‐Moya +2 more
wiley +1 more source
Педиатрическая фармакологияBackground. Niemann–Pick disease type C is a multisystem orphan disease caused by mutations in the NPC1 and NPC2 genes and characterized by clinical polymorphism. The difficulties of managing such patients lie in the diagnosis and differential diagnostic
Nailya R. Mingacheva +4 more
doaj +1 more source