Results 201 to 210 of about 66,702 (306)

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4490-4515, October 2025.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye   +5 more
wiley   +1 more source

Dissolution Behavior of Nifedipine Sustained-release Preparations

open access: bronze, 1987
Kazuyuki Ueno   +3 more
openalex   +2 more sources

Nifedipine for hiccups

open access: yesJournal of Pain and Symptom Management, 1997
openaire   +2 more sources

The Cardiac Sodium Channel Safety Profile of Cenobamate at Therapeutic Concentrations: In Vitro Analyses

open access: yesClinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT The US Food and Drug Administration (FDA) issued a Drug Safety Communication for the antiseizure drug lamotrigine (Lamictal), warning of the risk of QRS prolongation and cardiac arrhythmias. The FDA also requested that other antiseizure medications with a similar mechanism of action (e.g., block of neuronal sodium channels), including ...
William J. Crumb Jr   +2 more
wiley   +1 more source

Nifedipine in the treatment of chilblains. [PDF]

open access: bronze, 1986
Pauline M. Dowd   +2 more
openalex   +1 more source

Sclerosing diseases of the skin

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 10, Page 1282-1300, October 2025.
Summary Sclerosing skin diseases comprise a group of distinct dermatological conditions characterized by fibrotic changes that may severely impair patients’ quality of life. These conditions often present with cutaneous manifestations and, in some cases, may extend to extracutaneous tissues, potentially resulting in significant morbidity and mortality.
Yasamin Kalantari   +4 more
wiley   +1 more source

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