Results 281 to 290 of about 93,808 (329)
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Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth
The Lancet, 1992The mechanism of gingival overgrowth associated with long-term use of nifedipine and of other drugs that affect calcium homoeostasis, such as cyclosporin and phenytoin, is unknown. With an ultrasensitive assay, we measured the pharmacokinetics of nifedipine in plasma and gingival crevicular fluid (GCF) of nine patients receiving this drug for angina ...
Janice S. Ellis +3 more
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Chitosan microspheres of nifedipine and nifedipine-cyclodextrin inclusion complexes
International Journal of Pharmaceutics, 1996Chitosan microspheres of nifedipine and nifedipine cyclodextrin complexes were prepared by the glutaraldehyde cross-linking of chitosan. Microspheres having different degrees of swelling were made by varying the cross-linking density. Drug incorporation efficiencies exceeding 70 % could be achieved for this drug.
Ivan Jalšenjak +3 more
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Pharmacokinetics of nifedipine.
International journal of clinical pharmacology research, 1985The pharmacokinetics of a slow-release formulation of nifedipine were studied following oral administration of a single 20 mg tablet in nine young male volunteers. Blood samples were collected and nifedipine concentrations analysed by gas liquid chromatography.
PASANISI, FABRIZIO +2 more
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Nifedipine in the treatment of hypertension
European Journal of Clinical Pharmacology, 1983Nifedipine, a calcium antagonist with a predominant vasodilator action, was evaluated for the treatment of hypertension. A 20 mg-tablet, with a slower absorption and a more sustained blood-level than provided by the 10 mg-capsule was administered to 20 patients. The duration of the trial was 20 weeks.
S. Blake +3 more
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Pharmacology of Nifedipine [PDF]
, 1975 This paper is a brief synopsis of the main pharmacological properties of nifedipine in connection with a concept of its hemodynamic action.
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Nifedipine in Antihypertensive Therapy
Archives of Internal Medicine, 1985To the Editor. —We read with interest the article by Evans et al 1 in the May 1984Archives. Their results are similar to ours in demonstrating nifedipine efficacy as a substitute for hydralazine and captopril in combination antihypertensive therapy. 2 Recently, McAreavey et al 3 suggested hydralazine as the best third-line drug.
Ehud Grossman +2 more
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Pharmacokinetics of nifedipine in Taiwanese
Biopharmaceutics & Drug Disposition, 2004AbstractTo elucidate the pharmacokinetics of nifedipine in Taiwanese, a retrospective review of nifedipine bioequivalence studies completed in Taiwan in the past 5 years was conducted. A total of 198 healthy male volunteers were given a single dose of a 10 mg Adalat® capsule as a reference drug after overnight fasting.
Yow Shieng Uang +3 more
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Nifedipine-Induced Hypokalemia
Drug Intelligence & Clinical Pharmacy, 1986Nifedipine, a calcium-channel blocking agent, has been reported to cause many side effects, particularly in the cardiovascular system. A case of nifedipine-induced hypokalemia is presented, with a discussion on the presumable mechanism involved in this phenomenon.
Shoshana Armon, Moshe Tishler
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Nifedipine and Agranulocytosis
Annals of Internal Medicine, 1983Excerpt To the editor: We write to report a case of agranulocytosis we believe was probably caused by nifedipine.
Richard H. Turner, Arnold J. Voth
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Nifedipine in Intestinal Colic
JAMA: The Journal of the American Medical Association, 1990To the Editor.— Nifedipine, a calcium channel blocking agent, relaxes smooth muscle and has been widely used for the treatment of coronary insufficiency and hypertension. Used for its spasmolytic effect, nifedipine has been found to be effective in relieving acute and recurrent urinary colic. 1 It exhibits relaxant activity in the intestinal tract and
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