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Pharmacology of Nifedipine [PDF]
, 1975 This paper is a brief synopsis of the main pharmacological properties of nifedipine in connection with a concept of its hemodynamic action.
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Pharmacokinetics of nifedipine in Taiwanese
Biopharmaceutics & Drug Disposition, 2004AbstractTo elucidate the pharmacokinetics of nifedipine in Taiwanese, a retrospective review of nifedipine bioequivalence studies completed in Taiwan in the past 5 years was conducted. A total of 198 healthy male volunteers were given a single dose of a 10 mg Adalat® capsule as a reference drug after overnight fasting.
Yow Shieng Uang +3 more
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Nifedipine-Induced Hypokalemia
Drug Intelligence & Clinical Pharmacy, 1986Nifedipine, a calcium-channel blocking agent, has been reported to cause many side effects, particularly in the cardiovascular system. A case of nifedipine-induced hypokalemia is presented, with a discussion on the presumable mechanism involved in this phenomenon.
Shoshana Armon, Moshe Tishler
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Nifedipine in Pheochromocytoma
Annals of Internal Medicine, 1986Excerpt To the editor: The calcium antagonist nifedipine has been shown to suppress symptoms in two patients with pheochromocytoma (1, 2) while decreasing urinary norepinephrine and vanillylmandeli...
Laurent Favre, Michel B. Vallotton
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Nifedipine and Agranulocytosis
Annals of Internal Medicine, 1983Excerpt To the editor: We write to report a case of agranulocytosis we believe was probably caused by nifedipine.
Richard H. Turner, Arnold J. Voth
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Nifedipine in Intestinal Colic
JAMA: The Journal of the American Medical Association, 1990To the Editor.— Nifedipine, a calcium channel blocking agent, relaxes smooth muscle and has been widely used for the treatment of coronary insufficiency and hypertension. Used for its spasmolytic effect, nifedipine has been found to be effective in relieving acute and recurrent urinary colic. 1 It exhibits relaxant activity in the intestinal tract and
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Nifedipine in the Treatment of Achalasia
Annals of Internal Medicine, 1982Excerpt Nifedipine acts by inhibiting the slow transmembrane calcium flux responsible for electromechanical coupling in cardiac and smooth muscle (1, 2).
Keith Berger, Richard W. McCallum
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Nifedipine for Hypertensive Emergencies
JAMA: The Journal of the American Medical Association, 1997To the Editor. —We read with interest the report of Dr Grossman and colleagues 1 and the accompanying Editorial by Dr Winker 2 on sublingual nifedipine capsules. We recently performed a systematic search of the available literature on the use of short-acting nifedipine preparations in hypertensive emergencies and reached different conclusions.
SEMPLICINI, ANDREA +1 more
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Nifedipine and Platelets in Preeclampsia
American Journal of Hypertension, 1988In addition to its antihypertensive properties, nifedipine inhibits platelet aggregation in vitro. Because increased platelet aggregation is a feature of preeclampsia, we have investigated nifedipine in this condition. Ten women at 31 +/- 2.8 weeks gestation, with blood pressure 162 +/- 18/102 +/- 10 mmHg (despite atenolol 200 mg/day) and proteinuria 2.
Lucy Butters +2 more
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Nifedipine and the conditioning response
The American Journal of Cardiology, 1984The effect of nifedipine (N) on conditioning was studied in 14 healthy sedentary men, aged 20 to 34 years. Subjects were ranked according to maximal oxygen consumption (VO2 max), paired, and 1 of each pair randomly assigned to take N, 20 mg, or placebo (C) 3 times daily.
H L Brammell +2 more
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