Results 171 to 180 of about 7,787 (204)
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Rat liver nuclear nifurtimox nitroreductase activity.
Research communications in molecular pathology and pharmacology, 1998Nifurtimox (Nfx) 4-[(5-nitrofurfurylidine)amino-3-methylthiomorpholine-1-1-di oxide] is a drug that is being used to treat American Trypanosomiasis (Chagas' disease). Nfx has serious toxic effects including mutagenic, reproductive and carcinogenic actions.
E G, de Toranzo +2 more
openaire +1 more source
Tolerance to nifurtimox and benznidazole in adult patients with chronic Chagas’ disease
Journal of Antimicrobial Chemotherapy, 2020Yves Jackson, François Chappuis
exaly
Adverse Events Associated with Nifurtimox Treatment for Chagas Disease in Children and Adults
Antimicrobial Agents and Chemotherapy, 2021Facundo Garcia-Bournissen
exaly
Nifurtimox Activation by Trypanosomal Type I Nitroreductases Generates Cytotoxic Nitrile Metabolites
Journal of Biological Chemistry, 2011Belinda S Hall +2 more
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Safety Profile of Nifurtimox for Treatment of Chagas Disease in the United States
Clinical Infectious Diseases, 2016Colin J Forsyth +2 more
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