Results 1 to 10 of about 69,881 (202)

Acyclovir-Induced Nephrotoxicity: The Protective Benefit of Curcumin

open access: yesEuropean Journal of Biology, 2021
Objective: Nephrotoxicity may decrease the clinical use of acyclovir (ACV). Curcumin (CUM) is used traditionally as treatments for some diseases. This study examined the protective effect of CUM against ACV-induced nephrotoxicity in rats.
Elias Adikwu, James Kemelayefa
doaj   +1 more source

Inhibitory potential of rutin on lipopolysaccharide-induced toxicity and inflammatory response of raw U937 cells and macrophages

open access: yesNotulae Scientia Biologicae, 2022
Rutin is an important flavonoid found in plants with enormous pharmacological activities in various experimental models while lipopolysaccharide is an amphipathic glycolipid with potent inflammatory activity.
Tebekeme OKOKO, Faith O. ROBERT
doaj   +1 more source

Protective role of glycine and kolaviron on lipopolysaccharide-induced alterations of raw U937 cells and U937-derived macrophages

open access: yesNotulae Scientia Biologicae, 2022
The effect of glycine and kolaviron on lipopolysaccharide-induced U937 cell damage and activation of U937-derived macrophages was studied. U937 cells were incubated with either glycine or kolaviron or both for 24 h before exposure to lipopolysaccharide.
Tebekeme OKOKO, Solomon A. NDONI
doaj   +1 more source

Coenzyme Q10 and resveratrol protect against paclitaxel-induced nephrotoxicity in rats [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2021
The clinical use of paclitaxel (PCL) may cause nephrotoxicity. Antioxidants have shown potential benefits in some disease conditions. This study examined the protective abilities of coenzyme Q10 (CoQ10) and resveratrol (RSV) against PCL-induced ...
Elias Adikwu   +2 more
doaj   +1 more source

Comparative application of derivative spectrophotometric and HPLC techniques for the simultaneous determination of lamivudine and tenofovir disoproxil fumarate in fixed-dose combined drugs

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background Lamivudine (LAM) and tenofovir disoproxil fumarate (TDF) are part of a fixed-dose combination (FDC) therapy recommended by WHO. Both drugs exhibit similar solubility in many solvent systems and tend to have overlapping spectra with maxima at ...
Edebi N. Vaikosen   +3 more
doaj   +1 more source

Niger Delta gravity-driven deformation above the relict Chain and Charcot oceanic fracture zones, Gulf of Guinea: Insights from analogue models [PDF]

open access: yes, 2015
The Niger Delta is a classic example of a passive margin delta that has gravitationally deformed above an overpressured shale decollement. The outboard Niger Delta clastic wedge, including the Akata Formation overpressured shale decollement, is ...
Frankowicz, Edyta   +2 more
core   +1 more source

Demographic and fertility transition in Nigeria; the progress made so far: a literature review

open access: yesBabcock University Medical Journal, 2022
Background: Nigeria, since its inception as a sovereign nation, has been plagued by population explosion. This may be due to factors that need to be addressed by the government and individuals alike such as fertility desires.
Abednigo Addah, Ebenezer Ikobho
doaj   +3 more sources

The Dynamics of Oil and Social Movements in the Niger Delta of Nigeria [PDF]

open access: yes, 2006
The discovery of oil in Nigeria since 1956 has inflicted a heavy burden on the local people of the Niger River Delta who have had to contend with the consequences of oil production.
Ojakorotu, Victor
core   +3 more sources

Sphingomonadaceae: Protective against breast cancer?

open access: yesBulletin of the National Research Centre, 2020
Background Breast cancer is the most common malignancy and one of the leading causes of cancer-linked deaths in women. The development of the mammary gland is regulated by oestrogen whose activities have also been linked with various diseases including ...
Ebidor Ufoumanefe Lawani-Luwaji   +1 more
doaj   +1 more source

Knowledge, Attitude and Use of Contraceptives Among Women of Reproductive Age in a Nigerian Rural Community

open access: yesInternational Journal of Medical Students, 2023
BACKGROUND: The use of contraception, encompassing various methods such as hormonal pills, condoms, intrauterine devices, and natural techniques like abstinence, plays a pivotal role in family planning and reproductive health.
Monica Anurika Gbuchie   +4 more
doaj   +1 more source

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