Intestinal fungi contribute to development of alcoholic liver disease [PDF]
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian +37 more
core +3 more sources
20 ABCD Study Environmental Correlates of Gray Space on Cognitive Performance Among Youth via NIH Toolbox [PDF]
Julia C. Harris +2 more
openalex +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes [PDF]
Funded by •ERC. Grant Number: 284167 •NIH. Grant Number: 1RO1DK0921127-01 •NWO.
Day, Ian +13 more
core +2 more sources
A-215 Calculated LDL-cholesterol: Comparability of the extended Martin-Hopkins,Sampson-NIH, Friedewald and four other equations in South African patients [PDF]
A Carelse +4 more
openalex +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Validating SCENTinel against the NIH Toolbox Odor Identification Test, Sniffin Sticks, and BSIT
Anne Rose Zola +3 more
openalex +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Dihydropyrimidine-thiones and clioquinol synergize to target beta-amyloid cellular pathologies through a metal-dependent mechanism [PDF]
The lack of therapies for neurodegenerative diseases arises from our incomplete understanding of their underlying cellular toxicities and the limited number of predictive model systems.
Barrasa, M. Inmaculada +9 more
core +1 more source
The State of the NIH BRAIN Initiative
The BRAIN Initiative arose from a grand challenge to “accelerate the development and application of new technologies that will enable researchers to produce dynamic pictures of the brain that show how individual brain cells and complex neural circuits ...
W. Koroshetz +16 more
semanticscholar +1 more source

