Results 131 to 140 of about 2,411,456 (284)

Retention in care: is it still a clinically useful indicator for monitoring long-term engagement in HIV care in the treat-all era? [PDF]

AIDS
Lujintanon S, Rebeiro PF, Althoff KN, Jones JL, Zalla LC, Haw NJL, Hogan BC, Hackstadt AJ, Yazdani E, Horberg MA, Moore RD, Edwards JK, Napravnik S, Colasanti JA, Marconi VC, Lam JO, Park LS, Gebo KA, Lesko CR, North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD).   +19 more
europepmc   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Among individuals who die of COVID-19, is the percentage who had diabetes actually higher than in those dying of other viral infections? [PDF]

Cardiovasc Diabetol Endocrinol Rep
Reddy NV, Pate V, Stürmer T, Wong R, Harper J, Reusch JE, Wilkins KJ, Tronieri J, Buse JB, Johnson SG, Bramante CT.   +10 more
europepmc   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Refining Genetic Instruments for Dietary Intake Mendelian Randomization Using Phenome-Wide Association Studies. [PDF]

Genet Epidemiol
Sutton KJ, Gervis JE, Jatoi M, Hwang LD, Hendricks AE, Ghosh D, Westerman KE, Cole JB.   +7 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Sex-related transcriptomic differences in idiopathic pulmonary fibrosis. [PDF]

Am J Respir Crit Care Med
Menon AA, Moll M, Pugashetti JV, Linderholm AL, Liu GY, Krishna R, Ma SF, Noth I, Hunninghake GM, Feghali-Bostwick C, Ghosh AJ.   +10 more
europepmc   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

P655: Improved representation of functional data in ClinVar

Genetics in Medicine Open
Melissa Landrum, Kuljeet Kaur, Shanmuga Chitipiralla, Guangfeng Song, Chunlei Liu, Zenith Maddipatla, Garth Brown, Chao Chen, Jennifer Hart, Douglas Hoffman, Wonhee Jang, Rama Maiti, Joseph Mitchell, Tayebeh Rezaie, George Riley, Jinpeng Yang, Andrew Russette, Brandi Kattman   +17 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source