Results 21 to 30 of about 1,189 (121)

A STUDY ON THE FUNCTION OF 14-3-3SIGMA IN REGULATING CANCER ENERGY METABOLISM [PDF]

open access: yes, 2012
Metabolic reprogramming has been shown to be a major cancer hallmark providing tumor cells with significant advantages for survival, proliferation, growth, metastasis and resistance against anti-cancer therapies.
Phan, Liem M, Phan, Liem M
core  

Peptidyl-prolyl cis/trans isomerases in GtoPdb v.2025.3 [PDF]

open access: yes
Peptidyl-prolyl cis/trans isomerases (PPIases) are an enzyme family which catalyse the cis/trans isomerisation of proline peptide bonds to promote the folding and re-folding of peptides and proteins.
Annett, Stephanie, Robson, Tracy
core   +2 more sources

Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. [PDF]

open access: yes, 2011
Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. Sebbene la disfunzione beta cellulare rivesta un ruolo di primaria importanza nel diabete di tipo 2, le informazioni ad
BUGLIANI, MARCO
core  

Complex and Multidimensional Lipid Raft Alterations in a Murine Model of Alzheimer's Disease [PDF]

open access: yes, 2010
Various animal models of Alzheimer's disease (AD) have been created to assist our appreciation of AD pathophysiology, as well as aid development of novel therapeutic strategies. Despite the discovery of mutated proteins that predict the development of AD,
Wayne Chadwick   +3 more
core   +1 more source

Identifikation und Charakterisierung zellulärer Zielproteine zur antiviralen Therapie der SARS-Coronavirus Infektion [PDF]

open access: yes, 2011
The severe acute respiratory syndrome (SARS) was first observed in the Chinese province Guangdong in November 2002. The disease quickly spread around the globe via air travelling and caused a worldwide epidemic.
Schöpf, Julia
core   +2 more sources

Biological implications of differential expression of mitochondrial-shaping proteins in Parkinson’s disease [PDF]

open access: yes, 2018
It has long been accepted that mitochondrial function and morphology is affected in Parkinson’s disease, and that mitochondrial function can be directly related to its morphology. So far, mitochondrial morphological alterations studies, in the context of
Aroso, M   +5 more
core   +1 more source

인체 유방암에서 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)과의 직접 결합을 통한 Nrf2의 안정화 연구 [PDF]

open access: yes, 2020
학위논문 (박사) -- 서울대학교 대학원 : 융합과학기술대학원 분자의학 및 바이오제약학과, 2020. 8. Surh Young-Joon.Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) specifically recognizes phosphorylated serine or threonine of a target protein and isomerizes the adjacent proline ...
Soma Saeidi
core  

Increased Inflammatory Gene Expression in Masseter Muscle of an Orthognathic Surgery Subject with Obstructive Sleep Apnea [PDF]

open access: yes, 2014
Objective: Obstructive sleep apnea (OSA) is defined by recurrent breathing cessations accompanied by a collapse of the pharyngeal airway. Co-morbid conditions include obesity, cardiovascular disease, diabetes, and in some cases, retrognathia and muscle ...
Conn, Karen Kandel
core   +1 more source

PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses [PDF]

open access: yes, 2020
Ataxia telangiectasia and Rad3-related protein (ATR) is a serine/threonine-protein kinase of the PI3K family and is well known for its key role in regulating DNA damage responses in the nucleus. In addition to its nuclear functions, ATR also was found to
Biswas, Himadri   +5 more
core   +1 more source

Liquid Chromatography – Mass Spectrometry for Protein Biomarker Discovery in Pancreatic Adenocarcinoma [PDF]

open access: yes, 2011
Pancreatic cancer has one of the lowest survival rates of all cancers, partly due to the difficulty of detection in its early stages. Recent developments in liquid chromatography – mass spectrometry (LC-MS) technology have made it possible to profile ...
Wehr, Angela Y
core   +1 more source

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