Results 21 to 30 of about 827 (92)
Apocrine glands are bystanders in hidradenitis suppurativa and their involvement is gender specific
Journal of the European Academy of Dermatology and Venereology, Volume 34, Issue 7, Page 1555-1563, July 2020., 2020 Abstract Background Apocrine glands have been long considered as the initial targeted skin compartment in hidradenitis suppurativa/acne inversa (HS). Objective Detection of apocrine gland involvement in HS. Methods Apocrine glands were isolated from skin biopsies of involved and uninvolved skin of HS patients (n = 16, females : males 1 : 1) by laser ...
C.C. Zouboulis +3 more
wiley +1 more source
Medicinal Research Reviews, Volume 40, Issue 3, Page 881-908, May 2020., 2020 Abstract The latency phenomenon produced by human immunodeficiency virus (HIV‐1) prevents viral clearance by current therapies, and consequently development of a cure for HIV‐1 disease represents a formidable challenge. Research over the past decade has resulted in identification of small molecules that are capable of exposing HIV‐1 latent reservoirs ...
Pargol Hashemi, Ivan Sadowski
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Engineered nanoparticles potentials in male reproduction
Andrology, Volume 13, Issue 4, Page 694-705, May 2025.Abstract Background The escalating prevalence of fertility problems in the aging population necessitates a comprehensive exploration of contributing factors, extending beyond environmental concerns, work‐related stress, and unhealthy lifestyles. Among these, the rising incidence of testicular disorders emerges as a pivotal determinant of fertility ...
Feifei Zhao +8 more
wiley +1 more source
Amyloid‐β in Alzheimer's disease: Structure, toxicity, distribution, treatment, and prospects
Ibrain, Volume 10, Issue 3, Page 266-289, Fall 2024.The formation, deposition, and toxicity of amyloid‐β (Aβ) are discussed in this article. Aβ is produced after amyloid precursor protein cleavage and chronologically aggregates into monomer, oligomer, fibril, and plaque. Geographical deposition of Aβ will cause synaptic dysfunction, mitochondrial dysfunction, inflammation, or neurodegeneration depending
Yifan Yu +3 more
wiley +1 more source
Is autism a PIN1 deficiency syndrome? A proposed etiological role for glyphosate
Journal of Neurochemistry, Volume 168, Issue 9, Page 2124-2146, September 2024.Peptidyl‐prolyl cis/trans isomerase, NIMA‐interacting 1 (PIN1) is a proline isomerase that plays many important roles in neurodevelopment. Low neuronal PIN1 expression is linked to many neurodegenerative diseases. We show here that many pathological characteristics of autism are also associated with low PIN1 expression. We describe the proposed process
Stephanie Seneff +2 more
wiley +1 more source
2020 Annual World Congress of the Pulmonary Vascular Research Institute
, 2021 Pulmonary Circulation, Volume 11, Issue 2, Page 1-75, April-June 2021.
wiley +1 more source
International Journal of Inflammation, Volume 2017, Issue 1, 2017., 2017 Toll‐like receptors (TLRs), part of the innate immune system that recognises molecular signatures, are important in the recognition of pathogenic components. However, when specific cellular contexts develop in which TLRs are inappropriately activated by self‐components, this may lead to sterile inflammation and result in the occurrence of autoimmunity.
Mark Farrugia +2 more
wiley +1 more source
Clinical Genetics, Volume 105, Issue 5, Page 459-469, May 2024.SHANK3 is the primary gene of chromosome 22q13.3 associated with the neurodevelopmental disorder Phelan McDermid syndrome. We show that at least six other genes of 22q13.3 have direct or indirect mechanistic overlap with SHANK3, supporting the view that terminal deletions in this region represent a single syndrome. Abstract Chromosome 22q13.3 deletion (
Andrew R. Mitz +2 more
wiley +1 more source
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase. [PDF]
Braz J Otorhinolaryngol, 2023 Chen H, Cai X, Du B, Cai J, Luo Z.
europepmc +1 more source